1 His_kinase#1
305-376 aa · 72 aa · 14.4% of protein
Raw token
His_kinase:305:9.94e-25:376:72:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0O59_RS00755
Histidine kinase, Classic
Clostridioides difficile · GCF_004314885
ClassHKTypeClassicLength501 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004314885#E0O59_RS00755Stable P2CS identifier used across views.
GenomeGCF_004314885Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length501 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 501 aa (34.5%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
396-496 aa · 101 aa · 20.2% of protein
Raw token
HATPase_c:396:0.00000314:496:107:109- Raw architecture: His_kinase:305:9.94e-25:376:72:80#HATPase_c:396:0.00000314:496:107:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_004314885::NZ_BIPD01000002.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span156-2473Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004314885::NZ_BIPD01000002.1::G00005Context members
E0O59_RS00755E0O59_RS00760
Partner locus tags
E0O59_RS00755E0O59_RS00760
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_021368000.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8RJ55Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8RJ55_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0O59_RS00755Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIPD01000002.1Sequence record reported by the local genomic context database.
Genomic interval156-1 661 nt1 506 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span156-2 473 ntGCF_004314885::NZ_BIPD01000002.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004314885::NZ_BIPD01000002.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIPD01000002.1All displayed genes belong to this local TCS context.
Neighborhood span156-2 473 nt2 318 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
156 nt2 473 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E0O59_RS00755GCF_004314885#E0O59_RS00755
HKClassicCurrent focus
156-1 661 nt · Forward (+)
E0O59_RS00760GCF_004314885#E0O59_RS00760
RRunclassified
1 775-2 473 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448805#QKI_RS15415Use this link to inspect the representative gene detail.
PFAM architectureCupin_2 + His_kinase2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1468511
Simplified PFAM architecture for HKOC_1468511
PFAM domain coverage: 136 / 501 aa (27.1%)
1 aa501 aa
Cupin_2His_kinase
- Simplified architecture: Cupin_2 + His_kinase
- Raw architecture: Cupin_2[35-96] | His_kinase[303-376]
- Domain count: 2
- Matched identifier: HKOC_1468511
- Positioned domains: Cupin_2 35-96 ; His_kinase 303-376
Cluster members and taxonomy
Representative gene: GCF_000448805#QKI_RS15415
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314885
AssemblyASM431488v1 · Scaffoldhaploid
Genome composition4 161 823 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 96 · HK 45 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key