1 HisKA#1
457-524 aa · 68 aa · 9.9% of protein
Raw token
HisKA:457:0.0000000000000189:524:68:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0O47_RS12690
Histidine kinase, Classic
Clostridioides difficile · GCF_004314645
ClassHKTypeClassicLength686 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004314645#E0O47_RS12690Stable P2CS identifier used across views.
GenomeGCF_004314645Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length686 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage162 / 686 aa (23.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa686 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
570-663 aa · 94 aa · 13.7% of protein
Raw token
HATPase_c:570:0.00000000000189:663:98:109- Raw architecture: HisKA:457:0.0000000000000189:524:68:64#HATPase_c:570:0.00000000000189:663:98:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_004314645::NZ_BIOR01000022.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span70960-73908Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004314645::NZ_BIOR01000022.1::G00039Context members
E0O47_RS12690E0O47_RS12700
Partner locus tags
E0O47_RS12690E0O47_RS12700
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021365583.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0O47_RS12690Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIOR01000022.1Sequence record reported by the local genomic context database.
Genomic interval70 960-73 020 nt2 061 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span70 960-73 908 ntGCF_004314645::NZ_BIOR01000022.1::G00039
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004314645::NZ_BIOR01000022.1::G00039Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIOR01000022.1All displayed genes belong to this local TCS context.
Neighborhood span70 960-73 908 nt2 949 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
70 960 nt73 908 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E0O47_RS12690GCF_004314645#E0O47_RS12690
HKClassicCurrent focus
70 960-73 020 nt · Reverse (-)
E0O47_RS12700GCF_004314645#E0O47_RS12700
RROmpR
73 216-73 908 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_001497755#BN3430_RS14660Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0801206
Simplified PFAM architecture for HKOC_0801206
PFAM domain coverage: 160 / 686 aa (23.3%)
1 aa686 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[457-524] | HATPase_c[571-662]
- Domain count: 2
- Matched identifier: HKOC_0801206
- Positioned domains: HisKA 457-524 ; HATPase_c 571-662
Cluster members and taxonomy
Representative gene: GCF_001497755#BN3430_RS14660
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314645
AssemblyASM431464v1 · Scaffoldhaploid
Genome composition4 157 644 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key