1 HisKA#1
309-375 aa · 67 aa · 12.6% of protein
Raw token
HisKA:309:0.0000000000000138:375:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0O25_RS00990
Histidine kinase, Classic
Clostridioides difficile · GCF_004314425
ClassHKTypeClassicLength530 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004314425#E0O25_RS00990Stable P2CS identifier used across views.
GenomeGCF_004314425Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length530 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 530 aa (28.9%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
428-513 aa · 86 aa · 16.2% of protein
Raw token
HATPase_c:428:0.0000000386:513:90:109- Raw architecture: HisKA:309:0.0000000000000138:375:67:64#HATPase_c:428:0.0000000386:513:90:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_004314425::NZ_BIOG01000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span209117-211394Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004314425::NZ_BIOG01000001.1::G00002Context members
E0O25_RS00985E0O25_RS00990
Partner locus tags
E0O25_RS00985E0O25_RS00990
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021381512.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0O25_RS00990Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIOG01000001.1Sequence record reported by the local genomic context database.
Genomic interval209 802-211 394 nt1 593 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span209 117-211 394 ntGCF_004314425::NZ_BIOG01000001.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004314425::NZ_BIOG01000001.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIOG01000001.1All displayed genes belong to this local TCS context.
Neighborhood span209 117-211 394 nt2 278 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
209 117 nt211 394 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E0O25_RS00985GCF_004314425#E0O25_RS00985
RROmpR
209 117-209 833 nt · Forward (+)
E0O25_RS00990GCF_004314425#E0O25_RS00990
HKClassicCurrent focus
209 802-211 394 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000448725#QAW_RS12370Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1355674
Simplified PFAM architecture for HKOC_1355674
PFAM domain coverage: 191 / 530 aa (36.0%)
1 aa530 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[255-295] | HisKA[310-375] | HATPase_c[427-510]
- Domain count: 3
- Matched identifier: HKOC_1355674
- Positioned domains: HAMP 255-295 ; HisKA 310-375 ; HATPase_c 427-510
Cluster members and taxonomy
Representative gene: GCF_000448725#QAW_RS12370
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314425
AssemblyASM431442v1 · Scaffoldhaploid
Genome composition4 094 126 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key