1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw token
HisKA:148:0.0000000000000742:211:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0O15_RS06325
Histidine kinase, Classic
Clostridioides difficile · GCF_004314385
ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_004314385#E0O15_RS06325Stable P2CS identifier used across views.
GenomeGCF_004314385Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa371 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw token
HATPase_c:260:3.91e-25:368:110:109- Raw architecture: HisKA:148:0.0000000000000742:211:64:64#HATPase_c:260:3.91e-25:368:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpentadGCF_004314385::NZ_BIOE01000006.1::G00023
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span182092-187816Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004314385::NZ_BIOE01000006.1::G00023Context members
E0O15_RS06305E0O15_RS06310E0O15_RS06315E0O15_RS06320E0O15_RS06325
Partner locus tags
E0O15_RS06305E0O15_RS06310E0O15_RS06315E0O15_RS06320E0O15_RS06325
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021397421.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0O15_RS06325Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIOE01000006.1Sequence record reported by the local genomic context database.
Genomic interval186 701-187 816 nt1 116 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span182 092-187 816 ntGCF_004314385::NZ_BIOE01000006.1::G00023
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004314385::NZ_BIOE01000006.1::G00023Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIOE01000006.1All displayed genes belong to this local TCS context.
Neighborhood span182 092-187 816 nt5 725 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
182 092 nt187 816 nt
Neighborhood gene cards
5 genes in the current local neighborhood.
E0O15_RS06305GCF_004314385#E0O15_RS06305
RROmpR
182 092-182 769 nt · Forward (+)
E0O15_RS06310GCF_004314385#E0O15_RS06310
HKClassic
182 841-184 856 nt · Forward (+)
E0O15_RS06315GCF_004314385#E0O15_RS06315
RROmpR
184 906-185 586 nt · Forward (+)
E0O15_RS06320GCF_004314385#E0O15_RS06320
RROmpR
185 967-186 665 nt · Forward (+)
E0O15_RS06325GCF_004314385#E0O15_RS06325
HKClassicCurrent focus
186 701-187 816 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000450145#QK3_RS16740Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2676374
Simplified PFAM architecture for HKOC_2676374
PFAM domain coverage: 174 / 371 aa (46.9%)
1 aa371 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[149-213] | HATPase_c[261-369]
- Domain count: 2
- Matched identifier: HKOC_2676374
- Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Representative gene: GCF_000450145#QK3_RS16740
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314385
AssemblyASM431438v1 · Scaffoldhaploid
Genome composition4 250 557 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 110 · HK 54 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key