1 PAS_8#1
179-216 aa · 38 aa · 6.8% of protein
Raw token
PAS_8:179:0.0000372:216:38:65P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0O21_RS18495
Histidine kinase, Classic
Clostridioides difficile · GCF_004314345
ClassHKTypeClassicLength559 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004314345#E0O21_RS18495Stable P2CS identifier used across views.
GenomeGCF_004314345Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
PAS_8HisKAHATPase_c
Protein length559 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage222 / 559 aa (39.7%)Merged over positioned domains only.
Domain description1 PAS_8,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa559 aa
Domain-by-domain annotation3 items
2 HisKA#2
302-373 aa · 72 aa · 12.9% of protein
Raw token
HisKA:302:0.00000000164:373:72:643 HATPase_c#3
421-532 aa · 112 aa · 20.0% of protein
Raw token
HATPase_c:421:3.09e-25:532:112:109- Raw architecture: PAS_8:179:0.0000372:216:38:65#HisKA:302:0.00000000164:373:72:64#HATPase_c:421:3.09e-25:532:112:109
- Domain description: 1 PAS_8,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_004314345::NZ_BIOC01000342.1::G00053
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1051-2730Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004314345::NZ_BIOC01000342.1::G00053Context members
E0O21_RS18495
Partner locus tags
E0O21_RS18495
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_254056402.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0O21_RS18495Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIOC01000342.1Sequence record reported by the local genomic context database.
Genomic interval1 051-2 730 nt1 680 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 051-2 730 ntGCF_004314345::NZ_BIOC01000342.1::G00053
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004314345::NZ_BIOC01000342.1::G00053Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIOC01000342.1All displayed genes belong to this local TCS context.
Neighborhood span1 051-2 730 nt1 680 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 051 nt2 730 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
E0O21_RS18495GCF_004314345#E0O21_RS18495
HKClassicCurrent focus
1 051-2 730 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004314345#E0O21_RS18495The current gene is the representative for this cluster.
PFAM architecturePAS_8 + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1262422
Simplified PFAM architecture for HKOC_1262422
PFAM domain coverage: 221 / 559 aa (39.5%)
1 aa559 aa
PAS_8HisKAHATPase_c
- Simplified architecture: PAS_8 + HisKA + HATPase_c
- Raw architecture: PAS_8[179-219] | HisKA[303-371] | HATPase_c[421-531]
- Domain count: 3
- Matched identifier: HKOC_1262422
- Positioned domains: PAS_8 179-219 ; HisKA 303-371 ; HATPase_c 421-531
Cluster members and taxonomy
Representative gene: GCF_004314345#E0O21_RS18495
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314345
AssemblyASM431434v1 · Scaffoldhaploid
Genome composition4 110 440 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 46 · RR 53CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key