Gene detail

E0O21_RS17395

Histidine kinase, Classic

Clostridioides difficile · GCF_004314345

ClassHKTypeClassicLength214 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004314345#E0O21_RS17395Stable P2CS identifier used across views.
GenomeGCF_004314345Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2081720Run 6 · 12 sequences · id 100% · cov 80%
External referencesWP_131006506.1 · MIST4 E0O21_RS17395RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length214 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage143 / 214 aa (66.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa214 aa
HisKA: 7-71 aa (65 aa)1HATPase_c: 117-194 aa (78 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
7-71 aa · 65 aa · 30.4% of protein
Raw tokenHisKA:7:0.000000777:71:65:64
2 HATPase_c#2
117-194 aa · 78 aa · 36.4% of protein
Raw tokenHATPase_c:117:0.00000226:194:90:109
  • Raw architecture: HisKA:7:0.000000777:71:65:64#HATPase_c:117:0.00000226:194:90:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_004314345::NZ_BIOC01000274.1::G00048
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span3890-4534Genomic interval covered by the local TCS group.
Context group IDGCF_004314345::NZ_BIOC01000274.1::G00048
Context members
E0O21_RS17395
Partner locus tags
E0O21_RS17395
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_131006506.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0O21_RS17395Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIOC01000274.1Sequence record reported by the local genomic context database.
Genomic interval3 890-4 534 nt645 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 890-4 534 ntGCF_004314345::NZ_BIOC01000274.1::G00048

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004314345::NZ_BIOC01000274.1::G00048

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIOC01000274.1All displayed genes belong to this local TCS context.
Neighborhood span3 890-4 534 nt645 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 890 nt4 534 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2081720Run 6 · HK · 12 sequences
Representative sequenceGCF_900243285#DBQ37_RS12670Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2081720

Simplified PFAM architecture for HKOC_2081720

PFAM domain coverage: 143 / 440 aa (32.5%)

1 aa440 aa
HisKA: 234-297 aaHisKAHATPase_c: 343-421 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[234-297] | HATPase_c[343-421]
  • Domain count: 2
  • Matched identifier: HKOC_2081720
  • Positioned domains: HisKA 234-297 ; HATPase_c 343-421
Cluster members and taxonomy
Visualization

Representative gene: GCF_900243285#DBQ37_RS12670

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314345
AssemblyASM431434v1 · Scaffoldhaploid
Genome composition4 110 440 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 46 · RR 53CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key