Gene detail

E0O21_RS13565

Histidine kinase, Classic

Clostridioides difficile · GCF_004314345

ClassHKTypeClassicLength267 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004314345#E0O21_RS13565Stable P2CS identifier used across views.
GenomeGCF_004314345Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2827958Run 6 · 60 sequences · id 100% · cov 80%
External referencesWP_254056392.1 · MIST4 E0O21_RS13565RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length267 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 267 aa (62.5%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa267 aa
HisKA: 48-113 aa (66 aa)1HATPase_c: 165-265 aa (101 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
48-113 aa · 66 aa · 24.7% of protein
Raw tokenHisKA:48:0.0000000937:113:66:64
2 HATPase_c#2
165-265 aa · 101 aa · 37.8% of protein
Raw tokenHATPase_c:165:4.82e-25:265:101:109
  • Raw architecture: HisKA:48:0.0000000937:113:66:64#HATPase_c:165:4.82e-25:265:101:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_004314345::NZ_BIOC01000157.1::G00036
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-805Genomic interval covered by the local TCS group.
Context group IDGCF_004314345::NZ_BIOC01000157.1::G00036
Context members
E0O21_RS13565
Partner locus tags
E0O21_RS13565
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_254056392.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0O21_RS13565Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIOC01000157.1Sequence record reported by the local genomic context database.
Genomic interval1-805 nt805 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-805 ntGCF_004314345::NZ_BIOC01000157.1::G00036

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004314345::NZ_BIOC01000157.1::G00036

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIOC01000157.1All displayed genes belong to this local TCS context.
Neighborhood span1-805 nt805 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt805 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2827958Run 6 · HK · 60 sequences
Representative sequenceGCF_000448725#QAW_RS10470Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2827958

Simplified PFAM architecture for HKOC_2827958

PFAM domain coverage: 173 / 343 aa (50.4%)

1 aa343 aa
HisKA: 124-189 aaHisKAHATPase_c: 236-342 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[124-189] | HATPase_c[236-342]
  • Domain count: 2
  • Matched identifier: HKOC_2827958
  • Positioned domains: HisKA 124-189 ; HATPase_c 236-342
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448725#QAW_RS10470

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314345
AssemblyASM431434v1 · Scaffoldhaploid
Genome composition4 110 440 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 46 · RR 53CheA 1 · PP 2
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key