Gene detail

E0O08_RS11080

Histidine kinase, Classic

Clostridioides difficile · GCF_004314225

ClassHKTypeClassicLength245 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004314225#E0O08_RS11080Stable P2CS identifier used across views.
GenomeGCF_004314225Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2453446Run 6 · 200 sequences · id 100% · cov 80%
External referencesWP_131005943.1 · MIST4 E0O08_RS11080RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length245 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage151 / 245 aa (61.6%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for E0O08_RS11080
Domain-by-domain annotation2 items
1 HisKA_3#1
46-111 aa · 66 aa · 26.9% of protein
Raw tokenHisKA_3:46:3.16e-20:111:67:68
2 HATPase_c#2
152-236 aa · 85 aa · 34.7% of protein
Raw tokenHATPase_c:152:0.0000000027:236:104:109
  • Raw architecture: HisKA_3:46:3.16e-20:111:67:68#HATPase_c:152:0.0000000027:236:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_004314225::NZ_BINW01000137.1::G00030
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1-1379Genomic interval covered by the local TCS group.
Context group IDGCF_004314225::NZ_BINW01000137.1::G00030
Context members
E0O08_RS11080E0O08_RS11085
Partner locus tags
E0O08_RS11080E0O08_RS11085
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_131005943.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0O08_RS11080Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BINW01000137.1Sequence record reported by the local genomic context database.
Genomic interval1-739 nt739 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-1 379 ntGCF_004314225::NZ_BINW01000137.1::G00030

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004314225::NZ_BINW01000137.1::G00030

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BINW01000137.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 379 nt1 379 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 379 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2453446Run 6 · HK · 200 sequences
Representative sequenceGCF_004318545#E0R11_RS17805Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2453446

Simplified PFAM architecture for HKOC_2453446

PFAM domain coverage: 150 / 399 aa (37.6%)

1 aa399 aa
HisKA_3: 200-264 aaHisKA_3HATPase_c: 306-390 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[200-264] | HATPase_c[306-390]
  • Domain count: 2
  • Matched identifier: HKOC_2453446
  • Positioned domains: HisKA_3 200-264 ; HATPase_c 306-390
Cluster members and taxonomy
Visualization

Representative gene: GCF_004318545#E0R11_RS17805

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314225
AssemblyASM431422v1 · Scaffoldhaploid
Genome composition3 988 122 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 93 · HK 46 · RR 46CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key