1 HAMP#1
158-224 aa · 67 aa · 15.2% of protein
Raw token
HAMP:158:0.000000000618:224:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0N89_RS05980
Histidine kinase, Classic
Clostridioides difficile · GCF_004314205
ClassHKTypeClassicLength442 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004314205#E0N89_RS05980Stable P2CS identifier used across views.
GenomeGCF_004314205Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length442 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage218 / 442 aa (49.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa442 aa
Domain-by-domain annotation3 items
2 HisKA#2
235-293 aa · 59 aa · 13.3% of protein
Raw token
HisKA:235:0.000000000212:293:59:643 HATPase_c#3
350-441 aa · 92 aa · 20.8% of protein
Raw token
HATPase_c:350:0.0000000152:441:108:109- Raw architecture: HAMP:158:0.000000000618:224:70:69#HisKA:235:0.000000000212:293:59:64#HATPase_c:350:0.0000000152:441:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_004314205::NZ_BINV01000010.1::G00016
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span3274-5299Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004314205::NZ_BINV01000010.1::G00016Context members
E0N89_RS05980E0N89_RS05985
Partner locus tags
E0N89_RS05980E0N89_RS05985
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_131036106.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0N89_RS05980Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BINV01000010.1Sequence record reported by the local genomic context database.
Genomic interval3 274-4 602 nt1 329 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span3 274-5 299 ntGCF_004314205::NZ_BINV01000010.1::G00016
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004314205::NZ_BINV01000010.1::G00016Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BINV01000010.1All displayed genes belong to this local TCS context.
Neighborhood span3 274-5 299 nt2 026 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
3 274 nt5 299 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E0N89_RS05980GCF_004314205#E0N89_RS05980
HKClassicCurrent focus
3 274-4 602 nt · Reverse (-)
E0N89_RS05985GCF_004314205#E0N89_RS05985
RROmpR
4 595-5 299 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004314205#E0N89_RS05980The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c_53 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2054262
Simplified PFAM architecture for HKOC_2054262
PFAM domain coverage: 169 / 442 aa (38.2%)
1 aa442 aa
HAMPHisKAHATPase_c_5
- Simplified architecture: HAMP + HisKA + HATPase_c_5
- Raw architecture: HAMP[179-223] | HisKA[237-293] | HATPase_c_5[372-438]
- Domain count: 3
- Matched identifier: HKOC_2054262
- Positioned domains: HAMP 179-223 ; HisKA 237-293 ; HATPase_c_5 372-438
Cluster members and taxonomy
Representative gene: GCF_004314205#E0N89_RS05980
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314205
AssemblyASM431420v1 · Scaffoldhaploid
Genome composition4 171 133 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key