Gene detail

E0N78_RS07215

Histidine kinase, Classic

Clostridioides difficile · GCF_004314105

ClassHKTypeClassicLength351 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004314105#E0N78_RS07215Stable P2CS identifier used across views.
GenomeGCF_004314105Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2793881Run 6 · 1 sequences · id 100% · cov 80% · representative
External referencesWP_131035297.1 · MIST4 E0N78_RS07215RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_2HATPase_c
Protein length351 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 351 aa (49.3%)Merged over positioned domains only.
Domain description1 HisKA_2,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa351 aa
HisKA_2: 158-232 aa (75 aa)1HATPase_c: 252-349 aa (98 aa)2
Domain-by-domain annotation2 items
1 HisKA_2#1
158-232 aa · 75 aa · 21.4% of protein
Raw tokenHisKA_2:158:4.72e-16:232:76:76
2 HATPase_c#2
252-349 aa · 98 aa · 27.9% of protein
Raw tokenHATPase_c:252:0.0000000959:349:114:109
  • Raw architecture: HisKA_2:158:4.72e-16:232:76:76#HATPase_c:252:0.0000000959:349:114:109
  • Domain description: 1 HisKA_2,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_004314105::NZ_BINQ01000065.1::G00010
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span11929-12984Genomic interval covered by the local TCS group.
Context group IDGCF_004314105::NZ_BINQ01000065.1::G00010
Context members
E0N78_RS07215
Partner locus tags
E0N78_RS07215
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_131035297.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0N78_RS07215Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BINQ01000065.1Sequence record reported by the local genomic context database.
Genomic interval11 929-12 984 nt1 056 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span11 929-12 984 ntGCF_004314105::NZ_BINQ01000065.1::G00010

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004314105::NZ_BINQ01000065.1::G00010

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BINQ01000065.1All displayed genes belong to this local TCS context.
Neighborhood span11 929-12 984 nt1 056 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
11 929 nt12 984 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2793881Run 6 · HK · 1 sequences
Representative sequenceGCF_004314105#E0N78_RS07215The current gene is the representative for this cluster.
PFAM architectureHisKA_2 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2793881

Simplified PFAM architecture for HKOC_2793881

PFAM domain coverage: 166 / 351 aa (47.3%)

1 aa351 aa
HisKA_2: 158-229 aaHisKA_2HATPase_c: 255-348 aaHATPase_c
HisKA_2HATPase_c
  • Simplified architecture: HisKA_2 + HATPase_c
  • Raw architecture: HisKA_2[158-229] | HATPase_c[255-348]
  • Domain count: 2
  • Matched identifier: HKOC_2793881
  • Positioned domains: HisKA_2 158-229 ; HATPase_c 255-348
Cluster members and taxonomy
Visualization

Representative gene: GCF_004314105#E0N78_RS07215

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314105
AssemblyASM431410v1 · Scaffoldhaploid
Genome composition3 951 788 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 87 · HK 44 · RR 43CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key