1 PAS_4#1
215-323 aa · 109 aa · 18.6% of protein
Raw token
PAS_4:215:0.000000000179:323:115:110P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0N78_RS03605
Histidine kinase, Classic
Clostridioides difficile · GCF_004314105
ClassHKTypeClassicLength587 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004314105#E0N78_RS03605Stable P2CS identifier used across views.
GenomeGCF_004314105Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
PAS_4HisKAHATPase_c
Protein length587 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage290 / 587 aa (49.4%)Merged over positioned domains only.
Domain description1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation3 items
2 HisKA#2
332-401 aa · 70 aa · 11.9% of protein
Raw token
HisKA:332:0.00000000000000134:401:70:643 HATPase_c#3
448-558 aa · 111 aa · 18.9% of protein
Raw token
HATPase_c:448:9.57e-28:558:111:109- Raw architecture: PAS_4:215:0.000000000179:323:115:110#HisKA:332:0.00000000000000134:401:70:64#HATPase_c:448:9.57e-28:558:111:109
- Domain description: 1 PAS_4,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_004314105::NZ_BINQ01000021.1::G00006
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span23167-24931Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004314105::NZ_BINQ01000021.1::G00006Context members
E0N78_RS03605
Partner locus tags
E0N78_RS03605
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_131035276.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0N78_RS03605Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BINQ01000021.1Sequence record reported by the local genomic context database.
Genomic interval23 167-24 931 nt1 765 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span23 167-24 931 ntGCF_004314105::NZ_BINQ01000021.1::G00006
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004314105::NZ_BINQ01000021.1::G00006Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BINQ01000021.1All displayed genes belong to this local TCS context.
Neighborhood span23 167-24 931 nt1 765 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
23 167 nt24 931 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
E0N78_RS03605GCF_004314105#E0N78_RS03605
HKClassicCurrent focus
23 167-24 931 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_033841335#SIK60_RS06780Use this link to inspect the representative gene detail.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0976756
Simplified PFAM architecture for HKOC_0976756
PFAM domain coverage: 290 / 619 aa (46.8%)
1 aa619 aa
PAS_4HisKAHATPase_c
- Simplified architecture: PAS_4 + HisKA + HATPase_c
- Raw architecture: PAS_4[247-355] | HisKA[364-433] | HATPase_c[480-590]
- Domain count: 3
- Matched identifier: HKOC_0976756
- Positioned domains: PAS_4 247-355 ; HisKA 364-433 ; HATPase_c 480-590
Cluster members and taxonomy
Representative gene: GCF_033841335#SIK60_RS06780
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314105
AssemblyASM431410v1 · Scaffoldhaploid
Genome composition3 951 788 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 87 · HK 44 · RR 43CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key