1 HAMP#1
62-131 aa · 70 aa · 18.6% of protein
Raw token
HAMP:62:0.000000000012:131:70:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0N78_RS00010
Histidine kinase, Classic
Clostridioides difficile · GCF_004314105
ClassHKTypeClassicLength376 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004314105#E0N78_RS00010Stable P2CS identifier used across views.
GenomeGCF_004314105Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length376 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 376 aa (65.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa376 aa
Domain-by-domain annotation3 items
2 HisKA#2
156-221 aa · 66 aa · 17.6% of protein
Raw token
HisKA:156:0.00000000000000422:221:66:643 HATPase_c#3
267-376 aa · 110 aa · 29.3% of protein
Raw token
HATPase_c:267:9.15e-18:376:111:109- Raw architecture: HAMP:62:0.000000000012:131:70:69#HisKA:156:0.00000000000000422:221:66:64#HATPase_c:267:9.15e-18:376:111:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_004314105::NZ_BINQ01000001.1::G00001
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span703-1833Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004314105::NZ_BINQ01000001.1::G00001Context members
E0N78_RS00010
Partner locus tags
E0N78_RS00010
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_131035260.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0N78_RS00010Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BINQ01000001.1Sequence record reported by the local genomic context database.
Genomic interval703-1 833 nt1 131 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span703-1 833 ntGCF_004314105::NZ_BINQ01000001.1::G00001
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004314105::NZ_BINQ01000001.1::G00001Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BINQ01000001.1All displayed genes belong to this local TCS context.
Neighborhood span703-1 833 nt1 131 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
703 nt1 833 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
E0N78_RS00010GCF_004314105#E0N78_RS00010
HKClassicCurrent focus
703-1 833 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004314105#E0N78_RS00010The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2643528
Simplified PFAM architecture for HKOC_2643528
PFAM domain coverage: 227 / 376 aa (60.4%)
1 aa376 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[79-131] | HisKA[156-221] | HATPase_c[268-375]
- Domain count: 3
- Matched identifier: HKOC_2643528
- Positioned domains: HAMP 79-131 ; HisKA 156-221 ; HATPase_c 268-375
Cluster members and taxonomy
Representative gene: GCF_004314105#E0N78_RS00010
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314105
AssemblyASM431410v1 · Scaffoldhaploid
Genome composition3 951 788 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 87 · HK 44 · RR 43CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key