1 HAMP#1
212-279 aa · 68 aa · 13.7% of protein
Raw token
HAMP:212:0.00000634:279:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0O11_RS14635
Histidine kinase, Classic
Clostridioides difficile · GCF_004314045
ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004314045#E0O11_RS14635Stable P2CS identifier used across views.
GenomeGCF_004314045Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 495 aa (46.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa495 aa
Domain-by-domain annotation3 items
2 HisKA#2
289-347 aa · 59 aa · 11.9% of protein
Raw token
HisKA:289:4.11e-17:347:59:643 HATPase_c#3
395-495 aa · 101 aa · 20.4% of protein
Raw token
HATPase_c:395:2.8e-27:495:106:109- Raw architecture: HAMP:212:0.00000634:279:68:69#HisKA:289:4.11e-17:347:59:64#HATPase_c:395:2.8e-27:495:106:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_004314045::NZ_BINN01000032.1::G00044
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span26094-28287Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004314045::NZ_BINN01000032.1::G00044Context members
E0O11_RS14635E0O11_RS14640
Partner locus tags
E0O11_RS14635E0O11_RS14640
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003437034.1Primary protein accession used for annex mappings.
UniProt accessionA0A031WG74Primary UniProt accession resolved in the annex database.
UniProt IDA0A031WG74_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0O11_RS14635Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BINN01000032.1Sequence record reported by the local genomic context database.
Genomic interval26 094-27 581 nt1 488 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span26 094-28 287 ntGCF_004314045::NZ_BINN01000032.1::G00044
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004314045::NZ_BINN01000032.1::G00044Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BINN01000032.1All displayed genes belong to this local TCS context.
Neighborhood span26 094-28 287 nt2 194 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
26 094 nt28 287 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E0O11_RS14635GCF_004314045#E0O11_RS14635
HKClassicCurrent focus
26 094-27 581 nt · Reverse (-)
E0O11_RS14640GCF_004314045#E0O11_RS14640
RROmpR
27 583-28 287 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155025#UAB_RS0205810Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1504291
Simplified PFAM architecture for HKOC_1504291
PFAM domain coverage: 161 / 495 aa (32.5%)
1 aa495 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[287-347] | HATPase_c[395-494]
- Domain count: 2
- Matched identifier: HKOC_1504291
- Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Representative gene: GCF_000155025#UAB_RS0205810
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314045
AssemblyASM431404v1 · Scaffoldhaploid
Genome composition4 158 367 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 47 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key