Gene detail

E0N82_RS06790

Histidine kinase, Classic

Clostridioides difficile · GCF_004314005

ClassHKTypeClassicLength586 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004314005#E0N82_RS06790Stable P2CS identifier used across views.
GenomeGCF_004314005Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0976756Run 6 · 247 sequences · id 100% · cov 80%
External referencesWP_131034605.1 · MIST4 E0N82_RS06790RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_4HisKAHATPase_c
Protein length586 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage290 / 586 aa (49.5%)Merged over positioned domains only.
Domain description1 PAS_4,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for E0N82_RS06790
Domain-by-domain annotation3 items
1 PAS_4#1
214-322 aa · 109 aa · 18.6% of protein
Raw tokenPAS_4:214:0.000000000181:322:115:110
2 HisKA#2
331-400 aa · 70 aa · 11.9% of protein
Raw tokenHisKA:331:0.00000000000000145:400:70:64
3 HATPase_c#3
447-557 aa · 111 aa · 18.9% of protein
Raw tokenHATPase_c:447:1.05e-27:557:111:109
  • Raw architecture: PAS_4:214:0.000000000181:322:115:110#HisKA:331:0.00000000000000145:400:70:64#HATPase_c:447:1.05e-27:557:111:109
  • Domain description: 1 PAS_4,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_004314005::NZ_BINL01000040.1::G00017
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-1763Genomic interval covered by the local TCS group.
Context group IDGCF_004314005::NZ_BINL01000040.1::G00017
Context members
E0N82_RS06790
Partner locus tags
E0N82_RS06790
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_131034605.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagE0N82_RS06790Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BINL01000040.1Sequence record reported by the local genomic context database.
Genomic interval1-1 763 nt1 763 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-1 763 ntGCF_004314005::NZ_BINL01000040.1::G00017

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_004314005::NZ_BINL01000040.1::G00017

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BINL01000040.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 763 nt1 763 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 763 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0976756Run 6 · HK · 247 sequences
Representative sequenceGCF_033841335#SIK60_RS06780Use this link to inspect the representative gene detail.
PFAM architecturePAS_4 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0976756

Simplified PFAM architecture for HKOC_0976756

PFAM domain coverage: 290 / 619 aa (46.8%)

1 aa619 aa
PAS_4: 247-355 aaPAS_4HisKA: 364-433 aaHisKAHATPase_c: 480-590 aaHATPase_c
PAS_4HisKAHATPase_c
  • Simplified architecture: PAS_4 + HisKA + HATPase_c
  • Raw architecture: PAS_4[247-355] | HisKA[364-433] | HATPase_c[480-590]
  • Domain count: 3
  • Matched identifier: HKOC_0976756
  • Positioned domains: PAS_4 247-355 ; HisKA 364-433 ; HATPase_c 480-590
Cluster members and taxonomy
Visualization

Representative gene: GCF_033841335#SIK60_RS06780

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_004314005
AssemblyASM431400v1 · Scaffoldhaploid
Genome composition3 985 032 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 90 · HK 45 · RR 45CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key