1 HisKA#1
134-200 aa · 67 aa · 18.9% of protein
Raw token
HisKA:134:0.0000000000000147:200:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0N70_RS18420
Histidine kinase, Classic
Clostridioides difficile · GCF_004313925
ClassHKTypeClassicLength355 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004313925#E0N70_RS18420Stable P2CS identifier used across views.
GenomeGCF_004313925Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length355 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage153 / 355 aa (43.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa355 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
253-338 aa · 86 aa · 24.2% of protein
Raw token
HATPase_c:253:0.0000000542:338:90:109- Raw architecture: HisKA:134:0.0000000000000147:200:67:64#HATPase_c:253:0.0000000542:338:90:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_004313925::NZ_BINH01000493.1::G00049
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span346-1415Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004313925::NZ_BINH01000493.1::G00049Context members
E0N70_RS18420
Partner locus tags
E0N70_RS18420
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_131000830.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0N70_RS18420Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BINH01000493.1Sequence record reported by the local genomic context database.
Genomic interval346-1 415 nt1 070 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span346-1 415 ntGCF_004313925::NZ_BINH01000493.1::G00049
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004313925::NZ_BINH01000493.1::G00049Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BINH01000493.1All displayed genes belong to this local TCS context.
Neighborhood span346-1 415 nt1 070 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
346 nt1 415 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
E0N70_RS18420GCF_004313925#E0N70_RS18420
HKClassicCurrent focus
346-1 415 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004313925#E0N70_RS18420The current gene is the representative for this cluster.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2776286
Simplified PFAM architecture for HKOC_2776286
PFAM domain coverage: 193 / 355 aa (54.4%)
1 aa355 aa
HAMPHisKAHATPase_c
- Simplified architecture: HAMP + HisKA + HATPase_c
- Raw architecture: HAMP[80-121] | HisKA[135-200] | HATPase_c[251-335]
- Domain count: 3
- Matched identifier: HKOC_2776286
- Positioned domains: HAMP 80-121 ; HisKA 135-200 ; HATPase_c 251-335
Cluster members and taxonomy
Representative gene: GCF_004313925#E0N70_RS18420
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004313925
AssemblyASM431392v1 · Scaffoldhaploid
Genome composition3 848 408 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 86 · HK 39 · RR 46CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key