1 HAMP#1
114-180 aa · 67 aa · 16.1% of protein
Raw token
HAMP:114:0.0000019:180:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0N70_RS13200
Histidine kinase, Classic
Clostridioides difficile · GCF_004313925
ClassHKTypeClassicLength415 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004313925#E0N70_RS13200Stable P2CS identifier used across views.
GenomeGCF_004313925Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length415 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 415 aa (58.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa415 aa
Domain-by-domain annotation3 items
2 HisKA#2
193-260 aa · 68 aa · 16.4% of protein
Raw token
HisKA:193:0.0000000000000223:260:68:643 HATPase_c#3
307-413 aa · 107 aa · 25.8% of protein
Raw token
HATPase_c:307:6.94e-27:413:108:109- Raw architecture: HAMP:114:0.0000019:180:69:69#HisKA:193:0.0000000000000223:260:68:64#HATPase_c:307:6.94e-27:413:108:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_004313925::NZ_BINH01000205.1::G00033
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span1-1248Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004313925::NZ_BINH01000205.1::G00033Context members
E0N70_RS13200
Partner locus tags
E0N70_RS13200
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_131000673.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0N70_RS13200Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BINH01000205.1Sequence record reported by the local genomic context database.
Genomic interval1-1 248 nt1 248 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-1 248 ntGCF_004313925::NZ_BINH01000205.1::G00033
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004313925::NZ_BINH01000205.1::G00033Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BINH01000205.1All displayed genes belong to this local TCS context.
Neighborhood span1-1 248 nt1 248 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt1 248 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
E0N70_RS13200GCF_004313925#E0N70_RS13200
HKClassicCurrent focus
1-1 248 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004313925#E0N70_RS13200The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2312374
Simplified PFAM architecture for HKOC_2312374
PFAM domain coverage: 172 / 415 aa (41.4%)
1 aa415 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[193-257] | HATPase_c[307-413]
- Domain count: 2
- Matched identifier: HKOC_2312374
- Positioned domains: HisKA 193-257 ; HATPase_c 307-413
Cluster members and taxonomy
Representative gene: GCF_004313925#E0N70_RS13200
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004313925
AssemblyASM431392v1 · Scaffoldhaploid
Genome composition3 848 408 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 86 · HK 39 · RR 46CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key