1 PAS#1
355-466 aa · 112 aa · 15.0% of protein
Raw token
PAS:355:0.0000613:466:114:113P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0N70_RS08485
Histidine kinase, Classic
Clostridioides difficile · GCF_004313925
ClassHKTypeClassicLength746 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004313925#E0N70_RS08485Stable P2CS identifier used across views.
GenomeGCF_004313925Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
PASHisKAHATPase_c
Protein length746 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage295 / 746 aa (39.5%)Merged over positioned domains only.
Domain description1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa746 aa
Domain-by-domain annotation3 items
2 HisKA#2
489-560 aa · 72 aa · 9.7% of protein
Raw token
HisKA:489:0.00000000000000794:560:72:643 HATPase_c#3
607-717 aa · 111 aa · 14.9% of protein
Raw token
HATPase_c:607:1.57e-31:717:111:109- Raw architecture: PAS:355:0.0000613:466:114:113#HisKA:489:0.00000000000000794:560:72:64#HATPase_c:607:1.57e-31:717:111:109
- Domain description: 1 PAS,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_004313925::NZ_BINH01000093.1::G00019
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span9275-11516Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004313925::NZ_BINH01000093.1::G00019Context members
E0N70_RS08485
Partner locus tags
E0N70_RS08485
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_131000607.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0N70_RS08485Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BINH01000093.1Sequence record reported by the local genomic context database.
Genomic interval9 275-11 516 nt2 242 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span9 275-11 516 ntGCF_004313925::NZ_BINH01000093.1::G00019
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004313925::NZ_BINH01000093.1::G00019Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BINH01000093.1All displayed genes belong to this local TCS context.
Neighborhood span9 275-11 516 nt2 242 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
9 275 nt11 516 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
E0N70_RS08485GCF_004313925#E0N70_RS08485
HKClassicCurrent focus
9 275-11 516 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004313925#E0N70_RS08485The current gene is the representative for this cluster.
PFAM architecturePAS_8 + PAS_8 + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0677720
Simplified PFAM architecture for HKOC_0677720
PFAM domain coverage: 277 / 746 aa (37.1%)
1 aa746 aa
PAS_8PAS_8HisKAHATPase_c
- Simplified architecture: PAS_8 + PAS_8 + HisKA + HATPase_c
- Raw architecture: PAS_8[137-189] | PAS_8[355-395] | HisKA[489-560] | HATPase_c[607-717]
- Domain count: 4
- Matched identifier: HKOC_0677720
- Positioned domains: PAS_8 137-189 ; PAS_8 355-395 ; HisKA 489-560 ; HATPase_c 607-717
Cluster members and taxonomy
Representative gene: GCF_004313925#E0N70_RS08485
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004313925
AssemblyASM431392v1 · Scaffoldhaploid
Genome composition3 848 408 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 86 · HK 39 · RR 46CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key