1 GAF_3#1
130-253 aa · 124 aa · 24.9% of protein
Raw token
GAF_3:130:0.00000333:253:129:129P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0N73_RS16980
Histidine kinase, Classic
Clostridioides difficile · GCF_004313845
ClassHKTypeClassicLength497 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_004313845#E0N73_RS16980Stable P2CS identifier used across views.
GenomeGCF_004313845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
GAF_3HisKAHATPase_c
Protein length497 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage305 / 497 aa (61.4%)Merged over positioned domains only.
Domain description1 GAF_3,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa497 aa
Domain-by-domain annotation3 items
2 HisKA#2
273-340 aa · 68 aa · 13.7% of protein
Raw token
HisKA:273:0.00000000000406:340:68:643 HATPase_c#3
384-496 aa · 113 aa · 22.7% of protein
Raw token
HATPase_c:384:1.74e-30:496:113:109- Raw architecture: GAF_3:130:0.00000333:253:129:129#HisKA:273:0.00000000000406:340:68:64#HATPase_c:384:1.74e-30:496:113:109
- Domain description: 1 GAF_3,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_004313845::NZ_BIND01000334.1::G00049
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1-2227Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004313845::NZ_BIND01000334.1::G00049Context members
E0N73_RS16980E0N73_RS16985
Partner locus tags
E0N73_RS16980E0N73_RS16985
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_131084029.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0N73_RS16980Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIND01000334.1Sequence record reported by the local genomic context database.
Genomic interval1-1 495 nt1 495 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1-2 227 ntGCF_004313845::NZ_BIND01000334.1::G00049
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004313845::NZ_BIND01000334.1::G00049Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIND01000334.1All displayed genes belong to this local TCS context.
Neighborhood span1-2 227 nt2 227 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 nt2 227 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
E0N73_RS16980GCF_004313845#E0N73_RS16980
HKClassicCurrent focus
1-1 495 nt · Forward (+)
E0N73_RS16985GCF_004313845#E0N73_RS16985
RROmpR
1 529-2 227 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS09955Use this link to inspect the representative gene detail.
PFAM architectureKdpD + DUF4118 + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0405628
Simplified PFAM architecture for HKOC_0405628
PFAM domain coverage: 494 / 900 aa (54.9%)
1 aa900 aa
KdpDDUF4118HisKAHATPase_c
- Simplified architecture: KdpD + DUF4118 + HisKA + HATPase_c
- Raw architecture: KdpD[22-230] | DUF4118[409-514] | HisKA[676-743] | HATPase_c[788-898]
- Domain count: 4
- Matched identifier: HKOC_0405628
- Positioned domains: KdpD 22-230 ; DUF4118 409-514 ; HisKA 676-743 ; HATPase_c 788-898
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS09955
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004313845
AssemblyASM431384v1 · Scaffoldhaploid
Genome composition3 922 278 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 87 · HK 43 · RR 43CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key