1 HisKA#1
69-134 aa · 66 aa · 23.6% of protein
Raw token
HisKA:69:0.00000013:134:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
E0N73_RS14290
Histidine kinase, Classic
Clostridioides difficile · GCF_004313845
ClassHKTypeClassicLength280 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_004313845#E0N73_RS14290Stable P2CS identifier used across views.
GenomeGCF_004313845Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length280 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage163 / 280 aa (58.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa280 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
180-276 aa · 97 aa · 34.6% of protein
Raw token
HATPase_c:180:0.00000000000183:276:105:109- Raw architecture: HisKA:69:0.00000013:134:66:64#HATPase_c:180:0.00000000000183:276:105:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_004313845::NZ_BIND01000216.1::G00041
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span5482-6324Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_004313845::NZ_BIND01000216.1::G00041Context members
E0N73_RS14290
Partner locus tags
E0N73_RS14290
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_236877102.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagE0N73_RS14290Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_BIND01000216.1Sequence record reported by the local genomic context database.
Genomic interval5 482-6 324 nt843 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span5 482-6 324 ntGCF_004313845::NZ_BIND01000216.1::G00041
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_004313845::NZ_BIND01000216.1::G00041Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_BIND01000216.1All displayed genes belong to this local TCS context.
Neighborhood span5 482-6 324 nt843 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 482 nt6 324 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
E0N73_RS14290GCF_004313845#E0N73_RS14290
HKClassicCurrent focus
5 482-6 324 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_004313845#E0N73_RS14290The current gene is the representative for this cluster.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2902023
Simplified PFAM architecture for HKOC_2902023
PFAM domain coverage: 161 / 280 aa (57.5%)
1 aa280 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[70-133] | HATPase_c[180-276]
- Domain count: 2
- Matched identifier: HKOC_2902023
- Positioned domains: HisKA 70-133 ; HATPase_c 180-276
Cluster members and taxonomy
Representative gene: GCF_004313845#E0N73_RS14290
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_004313845
AssemblyASM431384v1 · Scaffoldhaploid
Genome composition3 922 278 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 87 · HK 43 · RR 43CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key