Gene detail

EGL89_RS15700

Histidine kinase, Classic

Clostridioides difficile · GCF_003863255

ClassHKTypeClassicLength467 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003863255#EGL89_RS15700Stable P2CS identifier used across views.
GenomeGCF_003863255Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1747748Run 6 · 617 sequences · id 100% · cov 80%
External referencesWP_009896818.1 · A0A9X8WPZ2 · MIST4 EGL89_RS15700RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length467 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage242 / 467 aa (51.8%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa467 aa
HAMP: 166-232 aa (67 aa)1HisKA: 245-312 aa (68 aa)2HATPase_c: 359-465 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
166-232 aa · 67 aa · 14.3% of protein
Raw tokenHAMP:166:0.0000039:232:69:69
2 HisKA#2
245-312 aa · 68 aa · 14.6% of protein
Raw tokenHisKA:245:0.0000000000000205:312:68:64
3 HATPase_c#3
359-465 aa · 107 aa · 22.9% of protein
Raw tokenHATPase_c:359:1.03e-26:465:108:109
  • Raw architecture: HAMP:166:0.0000039:232:69:69#HisKA:245:0.0000000000000205:312:68:64#HATPase_c:359:1.03e-26:465:108:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003863255::NZ_RQZY01000426.1::G00054
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2324-4456Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGL89_15700RefSeq proteinWP_009896818.1
Context group IDGCF_003863255::NZ_RQZY01000426.1::G00054
Context members
EGL89_RS15700EGL89_RS15705
Partner locus tags
EGL89_RS15700EGL89_RS15705
Partner old locus tags
EGL89_15700EGL89_15705
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009896818.1Primary protein accession used for annex mappings.
UniProt accessionA0A9X8WPZ2Primary UniProt accession resolved in the annex database.
UniProt IDA0A9X8WPZ2_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEGL89_RS15700Primary locus identifier stored in the genes table.
Old locus tagEGL89_15700Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RQZY01000426.1Sequence record reported by the local genomic context database.
Genomic interval2 324-3 727 nt1 404 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 324-4 456 ntGCF_003863255::NZ_RQZY01000426.1::G00054

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003863255::NZ_RQZY01000426.1::G00054

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RQZY01000426.1All displayed genes belong to this local TCS context.
Neighborhood span2 324-4 456 nt2 133 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 324 nt4 456 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EGL89_RS15700GCF_003863255#EGL89_RS15700
HKClassicCurrent focus

2 324-3 727 nt · Reverse (-)

Old locus EGL89_15700RefSeq WP_009896818.1
EGL89_RS15705GCF_003863255#EGL89_RS15705
RROmpR

3 731-4 456 nt · Reverse (-)

Old locus EGL89_15705RefSeq WP_004454491.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1747748Run 6 · HK · 617 sequences
Representative sequenceGCF_000154625#QAB_RS0210610Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1747748

Simplified PFAM architecture for HKOC_1747748

PFAM domain coverage: 172 / 467 aa (36.8%)

1 aa467 aa
HisKA: 245-309 aaHisKAHATPase_c: 359-465 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-309] | HATPase_c[359-465]
  • Domain count: 2
  • Matched identifier: HKOC_1747748
  • Positioned domains: HisKA 245-309 ; HATPase_c 359-465
Cluster members and taxonomy
Visualization

Representative gene: GCF_000154625#QAB_RS0210610

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003863255
AssemblyASM386325v1 · Contighaploid
Genome composition4 057 516 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 48 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key