Gene detail

EGM01_RS18885

Histidine kinase, Classic

Clostridioides difficile · GCF_003863195

ClassHKTypeClassicLength498 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_003863195#EGM01_RS18885Stable P2CS identifier used across views.
GenomeGCF_003863195Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1338482Run 6 · 2212 sequences · id 100% · cov 80%
External referencesWP_125028596.1 · MIST4 EGM01_RS18885RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length498 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage150 / 498 aa (30.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa498 aa
HisKA: 304-371 aa (68 aa)1HATPase_c: 416-497 aa (82 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
304-371 aa · 68 aa · 13.7% of protein
Raw tokenHisKA:304:0.000000000000249:371:68:64
2 HATPase_c#2
416-497 aa · 82 aa · 16.5% of protein
Raw tokenHATPase_c:416:6.17e-21:497:82:109
  • Raw architecture: HisKA:304:0.000000000000249:371:68:64#HATPase_c:416:6.17e-21:497:82:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_003863195::NZ_RRAK01000240.1::G00062
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span7852-9345Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGM01_18895RefSeq proteinWP_125028596.1
Context group IDGCF_003863195::NZ_RRAK01000240.1::G00062
Context members
EGM01_RS18885
Partner locus tags
EGM01_RS18885
Partner old locus tags
EGM01_18895
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_125028596.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEGM01_RS18885Primary locus identifier stored in the genes table.
Old locus tagEGM01_18895Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RRAK01000240.1Sequence record reported by the local genomic context database.
Genomic interval7 852-9 345 nt1 494 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span7 852-9 345 ntGCF_003863195::NZ_RRAK01000240.1::G00062

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003863195::NZ_RRAK01000240.1::G00062

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RRAK01000240.1All displayed genes belong to this local TCS context.
Neighborhood span7 852-9 345 nt1 494 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
7 852 nt9 345 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

EGM01_RS18885GCF_003863195#EGM01_RS18885
HKClassicCurrent focus

7 852-9 345 nt · Forward (+)

Old locus EGM01_18895RefSeq WP_125028596.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1338482Run 6 · HK · 2212 sequences
Representative sequenceGCF_000003215#QAC_RS0202670Use this link to inspect the representative gene detail.
PFAM architectureDUF4118 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1338482

Simplified PFAM architecture for HKOC_1338482

PFAM domain coverage: 286 / 535 aa (53.5%)

1 aa535 aa
DUF4118: 32-139 aaDUF4118HisKA: 304-371 aaHisKAHATPase_c: 416-525 aaHATPase_c
DUF4118HisKAHATPase_c
  • Simplified architecture: DUF4118 + HisKA + HATPase_c
  • Raw architecture: DUF4118[32-139] | HisKA[304-371] | HATPase_c[416-525]
  • Domain count: 3
  • Matched identifier: HKOC_1338482
  • Positioned domains: DUF4118 32-139 ; HisKA 304-371 ; HATPase_c 416-525
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0202670

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003863195
AssemblyASM386319v1 · Contighaploid
Genome composition4 090 418 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 49 · RR 55CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key