1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw token
HisKA:148:0.00000000000008:211:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EGM12_RS04425
Histidine kinase, Classic
Clostridioides difficile · GCF_003863145
ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_003863145#EGM12_RS04425Stable P2CS identifier used across views.
GenomeGCF_003863145Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa371 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw token
HATPase_c:260:4.62e-25:368:110:109- Raw architecture: HisKA:148:0.00000000000008:211:64:64#HATPase_c:260:4.62e-25:368:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpentadGCF_003863145::NZ_RRAV01000007.1::G00019
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span191963-197688Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGM12_04425RefSeq proteinWP_009891726.1
Context group ID
GCF_003863145::NZ_RRAV01000007.1::G00019Context members
EGM12_RS04405EGM12_RS04410EGM12_RS04415EGM12_RS04420EGM12_RS04425
Partner locus tags
EGM12_RS04405EGM12_RS04410EGM12_RS04415EGM12_RS04420EGM12_RS04425
Partner old locus tags
EGM12_04405EGM12_04410EGM12_04415EGM12_04420EGM12_04425
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009891726.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R1N1Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R1N1_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEGM12_RS04425Primary locus identifier stored in the genes table.
Old locus tagEGM12_04425Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RRAV01000007.1Sequence record reported by the local genomic context database.
Genomic interval196 573-197 688 nt1 116 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span191 963-197 688 ntGCF_003863145::NZ_RRAV01000007.1::G00019
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003863145::NZ_RRAV01000007.1::G00019Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RRAV01000007.1All displayed genes belong to this local TCS context.
Neighborhood span191 963-197 688 nt5 726 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
191 963 nt197 688 nt
Neighborhood gene cards
5 genes in the current local neighborhood.
EGM12_RS04405GCF_003863145#EGM12_RS04405
RROmpR
191 963-192 640 nt · Forward (+)
EGM12_RS04410GCF_003863145#EGM12_RS04410
HKClassic
192 712-194 727 nt · Forward (+)
EGM12_RS04415GCF_003863145#EGM12_RS04415
RROmpR
194 777-195 457 nt · Forward (+)
EGM12_RS04420GCF_003863145#EGM12_RS04420
RROmpR
195 839-196 537 nt · Forward (+)
EGM12_RS04425GCF_003863145#EGM12_RS04425
HKClassicCurrent focus
196 573-197 688 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0216515Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2676088
Simplified PFAM architecture for HKOC_2676088
PFAM domain coverage: 174 / 371 aa (46.9%)
1 aa371 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[149-213] | HATPase_c[261-369]
- Domain count: 2
- Matched identifier: HKOC_2676088
- Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0216515
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003863145
AssemblyASM386314v1 · Contighaploid
Genome composition4 087 059 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 106 · HK 50 · RR 56CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key