Gene detail

EGM08_RS05930

Histidine kinase, Classic

Clostridioides difficile · GCF_003863135

ClassHKTypeClassicLength432 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003863135#EGM08_RS05930Stable P2CS identifier used across views.
GenomeGCF_003863135Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2032570Run 6 · 146 sequences · id 100% · cov 80%
External referencesWP_032509604.1 · MIST4 EGM08_RS05930RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length432 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 432 aa (37.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa432 aa
HisKA: 214-274 aa (61 aa)1HATPase_c: 330-429 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
214-274 aa · 61 aa · 14.1% of protein
Raw tokenHisKA:214:0.0000000000632:274:61:64
2 HATPase_c#2
330-429 aa · 100 aa · 23.1% of protein
Raw tokenHATPase_c:330:8.99e-25:429:100:109
  • Raw architecture: HisKA:214:0.0000000000632:274:61:64#HATPase_c:330:8.99e-25:429:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003863135::NZ_RRAR01000007.1::G00019
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span561943-563954Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGM08_05930RefSeq proteinWP_032509604.1
Context group IDGCF_003863135::NZ_RRAR01000007.1::G00019
Context members
EGM08_RS05930EGM08_RS05935
Partner locus tags
EGM08_RS05930EGM08_RS05935
Partner old locus tags
EGM08_05930EGM08_05935
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_032509604.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEGM08_RS05930Primary locus identifier stored in the genes table.
Old locus tagEGM08_05930Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RRAR01000007.1Sequence record reported by the local genomic context database.
Genomic interval561 943-563 241 nt1 299 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span561 943-563 954 ntGCF_003863135::NZ_RRAR01000007.1::G00019

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003863135::NZ_RRAR01000007.1::G00019

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RRAR01000007.1All displayed genes belong to this local TCS context.
Neighborhood span561 943-563 954 nt2 012 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
561 943 nt563 954 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EGM08_RS05930GCF_003863135#EGM08_RS05930
HKClassicCurrent focus

561 943-563 241 nt · Reverse (-)

Old locus EGM08_05930RefSeq WP_032509604.1
EGM08_RS05935GCF_003863135#EGM08_RS05935
RROmpR

563 247-563 954 nt · Reverse (-)

Old locus EGM08_05935RefSeq WP_021359503.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2032570Run 6 · HK · 146 sequences
Representative sequenceGCF_000449985#QIK_RS13790Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2032570

Simplified PFAM architecture for HKOC_2032570

PFAM domain coverage: 166 / 444 aa (37.4%)

1 aa444 aa
HisKA: 225-286 aaHisKAHATPase_c: 338-441 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[225-286] | HATPase_c[338-441]
  • Domain count: 2
  • Matched identifier: HKOC_2032570
  • Positioned domains: HisKA 225-286 ; HATPase_c 338-441
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449985#QIK_RS13790

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003863135
AssemblyASM386313v1 · Contighaploid
Genome composition4 115 223 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 100 · HK 48 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key