1 HAMP#1
212-279 aa · 68 aa · 13.7% of protein
Raw token
HAMP:212:0.00000662:279:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EGL74_RS02250
Histidine kinase, Classic
Clostridioides difficile · GCF_003863105
ClassHKTypeClassicLength495 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003863105#EGL74_RS02250Stable P2CS identifier used across views.
GenomeGCF_003863105Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length495 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage228 / 495 aa (46.1%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation3 items
2 HisKA#2
289-347 aa · 59 aa · 11.9% of protein
Raw token
HisKA:289:3.94e-17:347:59:643 HATPase_c#3
395-495 aa · 101 aa · 20.4% of protein
Raw token
HATPase_c:395:2.65e-27:495:106:109- Raw architecture: HAMP:212:0.00000662:279:68:69#HisKA:289:3.94e-17:347:59:64#HATPase_c:395:2.65e-27:495:106:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003863105::NZ_RQZJ01000004.1::G00005
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span25935-28128Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGL74_02250RefSeq proteinWP_009895965.1
Context group ID
GCF_003863105::NZ_RQZJ01000004.1::G00005Context members
EGL74_RS02250EGL74_RS02255
Partner locus tags
EGL74_RS02250EGL74_RS02255
Partner old locus tags
EGL74_02250EGL74_02255
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_009895965.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEGL74_RS02250Primary locus identifier stored in the genes table.
Old locus tagEGL74_02250Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RQZJ01000004.1Sequence record reported by the local genomic context database.
Genomic interval25 935-27 422 nt1 488 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span25 935-28 128 ntGCF_003863105::NZ_RQZJ01000004.1::G00005
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003863105::NZ_RQZJ01000004.1::G00005Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RQZJ01000004.1All displayed genes belong to this local TCS context.
Neighborhood span25 935-28 128 nt2 194 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
25 935 nt28 128 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EGL74_RS02250GCF_003863105#EGL74_RS02250
HKClassicCurrent focus
25 935-27 422 nt · Reverse (-)
EGL74_RS02255GCF_003863105#EGL74_RS02255
RROmpR
27 424-28 128 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS05670Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1504248
Simplified PFAM architecture for HKOC_1504248
PFAM domain coverage: 161 / 495 aa (32.5%)
1 aa495 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[287-347] | HATPase_c[395-494]
- Domain count: 2
- Matched identifier: HKOC_1504248
- Positioned domains: HisKA 287-347 ; HATPase_c 395-494
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS05670
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003863105
AssemblyASM386310v1 · Contighaploid
Genome composition4 145 290 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key