Gene detail

EGL79_RS12085

Histidine kinase, Classic

Clostridioides difficile · GCF_003863075

ClassHKTypeClassicLength912 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_003863075#EGL79_RS12085Stable P2CS identifier used across views.
GenomeGCF_003863075Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0387802Run 6 · 346 sequences · id 100% · cov 80%
External referencesWP_009893087.1 · A0A0H3N2T5 · MIST4 EGL79_RS12085RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

PAS_8HisKAHATPase_c
Protein length912 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage222 / 912 aa (24.3%)Merged over positioned domains only.
Domain description1 PAS_8,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa912 aa
PAS_8: 532-569 aa (38 aa)1HisKA: 655-726 aa (72 aa)2HATPase_c: 774-885 aa (112 aa)3
Domain-by-domain annotation3 items
1 PAS_8#1
532-569 aa · 38 aa · 4.2% of protein
Raw tokenPAS_8:532:0.0000792:569:38:65
2 HisKA#2
655-726 aa · 72 aa · 7.9% of protein
Raw tokenHisKA:655:0.00000000195:726:72:64
3 HATPase_c#3
774-885 aa · 112 aa · 12.3% of protein
Raw tokenHATPase_c:774:2e-25:885:112:109
  • Raw architecture: PAS_8:532:0.0000792:569:38:65#HisKA:655:0.00000000195:726:72:64#HATPase_c:774:2e-25:885:112:109
  • Domain description: 1 PAS_8,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelorphanGCF_003863075::NZ_RQZO01000026.1::G00036
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span143023-145761Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGL79_12085RefSeq proteinWP_009893087.1
Context group IDGCF_003863075::NZ_RQZO01000026.1::G00036
Context members
EGL79_RS12085
Partner locus tags
EGL79_RS12085
Partner old locus tags
EGL79_12085
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009893087.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N2T5Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N2T5_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEGL79_RS12085Primary locus identifier stored in the genes table.
Old locus tagEGL79_12085Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RQZO01000026.1Sequence record reported by the local genomic context database.
Genomic interval143 023-145 761 nt2 739 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span143 023-145 761 ntGCF_003863075::NZ_RQZO01000026.1::G00036

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003863075::NZ_RQZO01000026.1::G00036

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RQZO01000026.1All displayed genes belong to this local TCS context.
Neighborhood span143 023-145 761 nt2 739 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
143 023 nt145 761 nt
Neighborhood gene cards

1 gene in the current local neighborhood.

EGL79_RS12085GCF_003863075#EGL79_RS12085
HKClassicCurrent focus

143 023-145 761 nt · Reverse (-)

Old locus EGL79_12085RefSeq WP_009893087.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0387802Run 6 · HK · 346 sequences
Representative sequenceGCF_000003215#QAC_RS0207350Use this link to inspect the representative gene detail.
PFAM architecturePAS_8 + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0387802

Simplified PFAM architecture for HKOC_0387802

PFAM domain coverage: 221 / 912 aa (24.2%)

1 aa912 aa
PAS_8: 532-572 aaHisKA: 656-724 aaHisKAHATPase_c: 774-884 aaHATPase_c
PAS_8HisKAHATPase_c
  • Simplified architecture: PAS_8 + HisKA + HATPase_c
  • Raw architecture: PAS_8[532-572] | HisKA[656-724] | HATPase_c[774-884]
  • Domain count: 3
  • Matched identifier: HKOC_0387802
  • Positioned domains: PAS_8 532-572 ; HisKA 656-724 ; HATPase_c 774-884
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0207350

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 346 total members. Page 1 / 7.

GCF_000003215#QAC_RS0207350 (representative)
QAC_RS0207350 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_000027105#CDR20291_RS07330
CDR20291_RS07330 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_000085225#CD196_RS07490
CD196_RS07490 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_000154645#UAA_RS0209215
UAA_RS0209215 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_000154665#QAD_RS0207535
QAD_RS0207535 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_000154685#AEC_RS0208820
AEC_RS0208820 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_000155045#EAA_RS0207250
EAA_RS0207250 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_000210455#CD7855_RS07320
CD7855_RS07320 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_000211235#CDBI1_RS07415
CDBI1_RS07415 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_000450765#QO5_RS08120
QO5_RS08120 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_000451065#QSC_RS07155
QSC_RS07155 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_000451785#QSO_RS06725
QSO_RS06725 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_000451885#QU5_RS07135
QU5_RS07135 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_000826625#BN2378_RS15950
BN2378_RS15950 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_001484885#CD26A54R_RS07305
CD26A54R_RS07305 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_001484895#CD26A54S_RS07385
CD26A54S_RS07385 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_001857645#HMPREF3082_RS16470
HMPREF3082_RS16470 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_001971835#BER28_RS07715
BER28_RS07715 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_001972015#BER29_RS07660
BER29_RS07660 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002300865#BGT97_RS20640
BGT97_RS20640 · HK · Classic
RefSeq: WP_143475552.1
GCF_002301945#BGU80_RS18685
BGU80_RS18685 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002302755#BGV00_RS18630
BGV00_RS18630 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002302765#BGV01_RS18790
BGV01_RS18790 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002303165#BGV24_RS20065
BGV24_RS20065 · HK · Classic
RefSeq: WP_236881296.1
GCF_002335485#NCKUH21_RS07120
NCKUH21_RS07120 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002812585#CWR57_RS07050
CWR57_RS07050 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002891495#AMR93_RS02425
AMR93_RS02425 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002945415#C3W74_RS07725
C3W74_RS07725 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002945515#C3L34_RS07710
C3L34_RS07710 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002945665#C3347_RS07730
C3347_RS07730 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002945755#C3348_RS07730
C3348_RS07730 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002945855#C3350_RS07740
C3350_RS07740 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002945945#C3349_RS07730
C3349_RS07730 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002946035#C3351_RS07740
C3351_RS07740 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002946135#C3352_RS07740
C3352_RS07740 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002946195#C3353_RS07730
C3353_RS07730 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_002954285#AMR92_RS09940
AMR92_RS09940 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_003313545#CDIF27638_RS07720
CDIF27638_RS07720 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_003313585#CDIF27640_RS07710
CDIF27640_RS07710 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_003482035#CDIF28196_RS07725
CDIF28196_RS07725 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_003597795#DA426_RS12195
DA426_RS12195 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_003597815#DA430_RS07715
DA430_RS07715 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_003597835#DA432_RS07670
DA432_RS07670 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_003597895#DA422_RS07615
DA422_RS07615 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_003597915#DA436_RS07665
DA436_RS07665 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_003625415#C0215_RS10235
C0215_RS10235 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_003625425#C0983_RS18975
C0983_RS18975 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_003625435#C0984_RS09870
C0984_RS09870 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_003862685#EGM06_RS02195
EGM06_RS02195 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5
GCF_003863035#EGL82_RS12680
EGL82_RS12680 · HK · Classic
RefSeq: WP_009893087.1
UniProt: A0A0H3N2T5

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003863075
AssemblyASM386307v1 · Contighaploid
Genome composition4 088 557 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key