Gene detail

EGM11_RS09535

Histidine kinase, Classic

Clostridioides difficile · GCF_003863055

ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003863055#EGM11_RS09535Stable P2CS identifier used across views.
GenomeGCF_003863055Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_1737534Run 6 · 343 sequences · id 100% · cov 80%
External referencesWP_009892732.1 · A0A0H3MZP2 · MIST4 EGM11_RS09535RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage175 / 468 aa (37.4%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for EGM11_RS09535
Domain-by-domain annotation2 items
1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw tokenHisKA:245:0.0000000000019:309:65:64
2 HATPase_c#2
357-466 aa · 110 aa · 23.5% of protein
Raw tokenHATPase_c:357:1.68e-17:466:111:109
  • Raw architecture: HisKA:245:0.0000000000019:309:65:64#HATPase_c:357:1.68e-17:466:111:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003863055::NZ_RRAU01000015.1::G00032
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span93804-95962Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGM11_09535RefSeq proteinWP_009892732.1
Context group IDGCF_003863055::NZ_RRAU01000015.1::G00032
Context members
EGM11_RS09535EGM11_RS09540
Partner locus tags
EGM11_RS09535EGM11_RS09540
Partner old locus tags
EGM11_09535EGM11_09540
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009892732.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3MZP2Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3MZP2_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEGM11_RS09535Primary locus identifier stored in the genes table.
Old locus tagEGM11_09535Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RRAU01000015.1Sequence record reported by the local genomic context database.
Genomic interval93 804-95 210 nt1 407 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span93 804-95 962 ntGCF_003863055::NZ_RRAU01000015.1::G00032

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003863055::NZ_RRAU01000015.1::G00032

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RRAU01000015.1All displayed genes belong to this local TCS context.
Neighborhood span93 804-95 962 nt2 159 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
93 804 nt95 962 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EGM11_RS09535GCF_003863055#EGM11_RS09535
HKClassicCurrent focus

93 804-95 210 nt · Reverse (-)

Old locus EGM11_09535RefSeq WP_009892732.1
EGM11_RS09540GCF_003863055#EGM11_RS09540
RROmpR

95 255-95 962 nt · Reverse (-)

Old locus EGM11_09540RefSeq WP_009888460.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_1737534Run 6 · HK · 343 sequences
Representative sequenceGCF_000003215#QAC_RS0203465Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_1737534

Simplified PFAM architecture for HKOC_1737534

PFAM domain coverage: 175 / 468 aa (37.4%)

1 aa468 aa
HisKA: 245-310 aaHisKAHATPase_c: 358-466 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[245-310] | HATPase_c[358-466]
  • Domain count: 2
  • Matched identifier: HKOC_1737534
  • Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0203465

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003863055
AssemblyASM386305v1 · Contighaploid
Genome composition4 073 138 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key