Gene detail

EGM11_RS04310

Histidine kinase, Classic

Clostridioides difficile · GCF_003863055

ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_003863055#EGM11_RS04310Stable P2CS identifier used across views.
GenomeGCF_003863055Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2676088Run 6 · 404 sequences · id 100% · cov 80%
External referencesWP_009891726.1 · A0AB74R1N1 · MIST4 EGM11_RS04310RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa371 aa
HisKA: 148-211 aa (64 aa)1HATPase_c: 260-368 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw tokenHisKA:148:0.00000000000008:211:64:64
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw tokenHATPase_c:260:4.62e-25:368:110:109
  • Raw architecture: HisKA:148:0.00000000000008:211:64:64#HATPase_c:260:4.62e-25:368:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_003863055::NZ_RRAU01000004.1::G00018
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span175909-181634Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGM11_04310RefSeq proteinWP_009891726.1
Context group IDGCF_003863055::NZ_RRAU01000004.1::G00018
Context members
EGM11_RS04290EGM11_RS04295EGM11_RS04300EGM11_RS04305EGM11_RS04310
Partner locus tags
EGM11_RS04290EGM11_RS04295EGM11_RS04300EGM11_RS04305EGM11_RS04310
Partner old locus tags
EGM11_04290EGM11_04295EGM11_04300EGM11_04305EGM11_04310

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009891726.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R1N1Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R1N1_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEGM11_RS04310Primary locus identifier stored in the genes table.
Old locus tagEGM11_04310Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RRAU01000004.1Sequence record reported by the local genomic context database.
Genomic interval180 519-181 634 nt1 116 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span175 909-181 634 ntGCF_003863055::NZ_RRAU01000004.1::G00018

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003863055::NZ_RRAU01000004.1::G00018

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RRAU01000004.1All displayed genes belong to this local TCS context.
Neighborhood span175 909-181 634 nt5 726 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
175 909 nt181 634 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

EGM11_RS04290GCF_003863055#EGM11_RS04290
RROmpR

175 909-176 586 nt · Forward (+)

Old locus EGM11_04290RefSeq WP_009891739.1
EGM11_RS04295GCF_003863055#EGM11_RS04295
HKClassic

176 658-178 673 nt · Forward (+)

Old locus EGM11_04295RefSeq WP_009893921.1
EGM11_RS04300GCF_003863055#EGM11_RS04300
RROmpR

178 723-179 403 nt · Forward (+)

Old locus EGM11_04300RefSeq WP_009891737.1
EGM11_RS04305GCF_003863055#EGM11_RS04305
RROmpR

179 785-180 483 nt · Forward (+)

Old locus EGM11_04305RefSeq WP_009891729.1
EGM11_RS04310GCF_003863055#EGM11_RS04310
HKClassicCurrent focus

180 519-181 634 nt · Forward (+)

Old locus EGM11_04310RefSeq WP_009891726.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2676088Run 6 · HK · 404 sequences
Representative sequenceGCF_000003215#QAC_RS0216515Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2676088

Simplified PFAM architecture for HKOC_2676088

PFAM domain coverage: 174 / 371 aa (46.9%)

1 aa371 aa
HisKA: 149-213 aaHisKAHATPase_c: 261-369 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[149-213] | HATPase_c[261-369]
  • Domain count: 2
  • Matched identifier: HKOC_2676088
  • Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0216515

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003863055
AssemblyASM386305v1 · Contighaploid
Genome composition4 073 138 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key