1 HAMP#1
144-211 aa · 68 aa · 15.4% of protein
Raw token
HAMP:144:0.00000017:211:68:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EGL90_RS00665
Histidine kinase, Classic
Clostridioides difficile · GCF_003862935
ClassHKTypeClassicLength442 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003862935#EGL90_RS00665Stable P2CS identifier used across views.
GenomeGCF_003862935Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPHisKAHATPase_c
Protein length442 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage231 / 442 aa (52.3%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa442 aa
Domain-by-domain annotation3 items
2 HisKA#2
231-296 aa · 66 aa · 14.9% of protein
Raw token
HisKA:231:0.000000266:296:66:643 HATPase_c#3
342-438 aa · 97 aa · 21.9% of protein
Raw token
HATPase_c:342:0.00000000000495:438:105:109- Raw architecture: HAMP:144:0.00000017:211:68:69#HisKA:231:0.000000266:296:66:64#HATPase_c:342:0.00000000000495:438:105:109
- Domain description: 1 HAMP,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003862935::NZ_RQZZ01000001.1::G00002
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span134861-136842Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGL90_00665RefSeq proteinWP_008790769.1
Context group ID
GCF_003862935::NZ_RQZZ01000001.1::G00002Context members
EGL90_RS00660EGL90_RS00665
Partner locus tags
EGL90_RS00660EGL90_RS00665
Partner old locus tags
EGL90_00660EGL90_00665
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_008790769.1Primary protein accession used for annex mappings.
UniProt accessionE7GFZ4Primary UniProt accession resolved in the annex database.
UniProt IDE7GFZ4_9FIRMDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEGL90_RS00665Primary locus identifier stored in the genes table.
Old locus tagEGL90_00665Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RQZZ01000001.1Sequence record reported by the local genomic context database.
Genomic interval135 514-136 842 nt1 329 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span134 861-136 842 ntGCF_003862935::NZ_RQZZ01000001.1::G00002
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003862935::NZ_RQZZ01000001.1::G00002Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RQZZ01000001.1All displayed genes belong to this local TCS context.
Neighborhood span134 861-136 842 nt1 982 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
134 861 nt136 842 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EGL90_RS00660GCF_003862935#EGL90_RS00660
RROmpR
134 861-135 517 nt · Forward (+)
EGL90_RS00665GCF_003862935#EGL90_RS00665
HKClassicCurrent focus
135 514-136 842 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000186525#HMPREF9488_RS18645Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2051524
Simplified PFAM architecture for HKOC_2051524
PFAM domain coverage: 161 / 442 aa (36.4%)
1 aa442 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[232-295] | HATPase_c[342-438]
- Domain count: 2
- Matched identifier: HKOC_2051524
- Positioned domains: HisKA 232-295 ; HATPase_c 342-438
Cluster members and taxonomy
Representative gene: GCF_000186525#HMPREF9488_RS18645
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003862935
AssemblyASM386293v1 · Contighaploid
Genome composition4 099 207 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key