Gene detail

EGL98_RS09740

Histidine kinase, Classic

Clostridioides difficile · GCF_003862815

ClassHKTypeClassicLength407 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003862815#EGL98_RS09740Stable P2CS identifier used across views.
GenomeGCF_003862815Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2380014Run 6 · 75 sequences · id 100% · cov 80%
External referencesWP_330363505.1 · MIST4 EGL98_RS09740RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length407 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage251 / 407 aa (61.7%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa407 aa
HAMP: 94-171 aa (78 aa)1HisKA: 183-248 aa (66 aa)2HATPase_c: 298-404 aa (107 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
94-171 aa · 78 aa · 19.2% of protein
Raw tokenHAMP:94:0.00000000532:171:78:69
2 HisKA#2
183-248 aa · 66 aa · 16.2% of protein
Raw tokenHisKA:183:0.00000000333:248:66:64
3 HATPase_c#3
298-404 aa · 107 aa · 26.3% of protein
Raw tokenHATPase_c:298:4.46e-26:404:107:109
  • Raw architecture: HAMP:94:0.00000000532:171:78:69#HisKA:183:0.00000000333:248:66:64#HATPase_c:298:4.46e-26:404:107:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003862815::NZ_RRAH01000020.1::G00036
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span40871-43006Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGL98_09735RefSeq proteinWP_330363505.1
Context group IDGCF_003862815::NZ_RRAH01000020.1::G00036
Context members
EGL98_RS09740EGL98_RS09745
Partner locus tags
EGL98_RS09740EGL98_RS09745
Partner old locus tags
EGL98_09735EGL98_09740
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_330363505.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEGL98_RS09740Primary locus identifier stored in the genes table.
Old locus tagEGL98_09735Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RRAH01000020.1Sequence record reported by the local genomic context database.
Genomic interval40 871-42 094 nt1 224 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span40 871-43 006 ntGCF_003862815::NZ_RRAH01000020.1::G00036

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003862815::NZ_RRAH01000020.1::G00036

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RRAH01000020.1All displayed genes belong to this local TCS context.
Neighborhood span40 871-43 006 nt2 136 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
40 871 nt43 006 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EGL98_RS09740GCF_003862815#EGL98_RS09740
HKClassicCurrent focus

40 871-42 094 nt · Reverse (-)

Old locus EGL98_09735RefSeq WP_330363505.1
EGL98_RS09745GCF_003862815#EGL98_RS09745
RROmpR

42 314-43 006 nt · Reverse (-)

Old locus EGL98_09740RefSeq WP_009901954.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2380014Run 6 · HK · 75 sequences
Representative sequenceGCF_000155025#UAB_RS0203575Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2380014

Simplified PFAM architecture for HKOC_2380014

PFAM domain coverage: 223 / 407 aa (54.8%)

1 aa407 aa
HAMP: 121-171 aaHAMPHisKA: 184-248 aaHisKAHATPase_c: 298-404 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[121-171] | HisKA[184-248] | HATPase_c[298-404]
  • Domain count: 3
  • Matched identifier: HKOC_2380014
  • Positioned domains: HAMP 121-171 ; HisKA 184-248 ; HATPase_c 298-404
Cluster members and taxonomy
Visualization

Representative gene: GCF_000155025#UAB_RS0203575

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003862815
AssemblyASM386281v1 · Contighaploid
Genome composition4 197 264 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 51CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key