Gene detail

EGL98_RS04490

Histidine kinase, Classic

Clostridioides difficile · GCF_003862815

ClassHKTypeClassicLength417 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003862815#EGL98_RS04490Stable P2CS identifier used across views.
GenomeGCF_003862815Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2293769Run 6 · 77 sequences · id 100% · cov 80%
External referencesWP_074067435.1 · MIST4 EGL98_RS04490RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length417 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 417 aa (40.0%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for EGL98_RS04490
Domain-by-domain annotation2 items
1 HisKA#1
199-258 aa · 60 aa · 14.4% of protein
Raw tokenHisKA:199:0.00000000116:258:60:64
2 HATPase_c#2
304-410 aa · 107 aa · 25.7% of protein
Raw tokenHATPase_c:304:2e-21:410:107:109
  • Raw architecture: HisKA:199:0.00000000116:258:60:64#HATPase_c:304:2e-21:410:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003862815::NZ_RRAH01000004.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span165053-166988Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGL98_04485RefSeq proteinWP_074067435.1
Context group IDGCF_003862815::NZ_RRAH01000004.1::G00011
Context members
EGL98_RS04485EGL98_RS04490
Partner locus tags
EGL98_RS04485EGL98_RS04490
Partner old locus tags
EGL98_04480EGL98_04485
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_074067435.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEGL98_RS04490Primary locus identifier stored in the genes table.
Old locus tagEGL98_04485Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RRAH01000004.1Sequence record reported by the local genomic context database.
Genomic interval165 735-166 988 nt1 254 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span165 053-166 988 ntGCF_003862815::NZ_RRAH01000004.1::G00011

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003862815::NZ_RRAH01000004.1::G00011

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RRAH01000004.1All displayed genes belong to this local TCS context.
Neighborhood span165 053-166 988 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
165 053 nt166 988 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EGL98_RS04485GCF_003862815#EGL98_RS04485
RROmpR

165 053-165 757 nt · Forward (+)

Old locus EGL98_04480RefSeq WP_021370306.1
EGL98_RS04490GCF_003862815#EGL98_RS04490
HKClassicCurrent focus

165 735-166 988 nt · Forward (+)

Old locus EGL98_04485RefSeq WP_074067435.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2293769Run 6 · HK · 77 sequences
Representative sequenceGCF_000449025#QCG_RS08285Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2293769

Simplified PFAM architecture for HKOC_2293769

PFAM domain coverage: 169 / 417 aa (40.5%)

1 aa417 aa
HisKA: 196-258 aaHisKAHATPase_c: 305-410 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[196-258] | HATPase_c[305-410]
  • Domain count: 2
  • Matched identifier: HKOC_2293769
  • Positioned domains: HisKA 196-258 ; HATPase_c 305-410
Cluster members and taxonomy
Visualization

Representative gene: GCF_000449025#QCG_RS08285

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003862815
AssemblyASM386281v1 · Contighaploid
Genome composition4 197 264 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 51CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key