1 HAMP#1
6-74 aa · 69 aa · 16.1% of protein
Raw token
HAMP:6:0.000000259:74:69:69P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EGL99_RS08855
Histidine kinase, Classic
Clostridioides difficile · GCF_003862785
ClassHKTypeClassicLength429 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003862785#EGL99_RS08855Stable P2CS identifier used across views.
GenomeGCF_003862785Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HAMPPASHisKAHATPase_c
Protein length429 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage347 / 429 aa (80.9%)Merged over positioned domains only.
Domain description1 HAMP,1 PAS,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa429 aa
Domain-by-domain annotation4 items
2 PAS#2
87-193 aa · 107 aa · 24.9% of protein
Raw token
PAS:87:0.000000779:193:113:1133 HisKA#3
202-268 aa · 67 aa · 15.6% of protein
Raw token
HisKA:202:3.14e-18:268:67:644 HATPase_c#4
319-422 aa · 104 aa · 24.2% of protein
Raw token
HATPase_c:319:3.66e-30:422:104:109- Raw architecture: HAMP:6:0.000000259:74:69:69#PAS:87:0.000000779:193:113:113#HisKA:202:3.14e-18:268:67:64#HATPase_c:319:3.66e-30:422:104:109
- Domain description: 1 HAMP,1 PAS,1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003862785::NZ_RRAI01000019.1::G00028
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span95916-97926Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGL99_08855RefSeq proteinWP_124984188.1
Context group ID
GCF_003862785::NZ_RRAI01000019.1::G00028Context members
EGL99_RS08855EGL99_RS08860
Partner locus tags
EGL99_RS08855EGL99_RS08860
Partner old locus tags
EGL99_08855EGL99_08860
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_124984188.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEGL99_RS08855Primary locus identifier stored in the genes table.
Old locus tagEGL99_08855Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RRAI01000019.1Sequence record reported by the local genomic context database.
Genomic interval95 916-97 205 nt1 290 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span95 916-97 926 ntGCF_003862785::NZ_RRAI01000019.1::G00028
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003862785::NZ_RRAI01000019.1::G00028Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RRAI01000019.1All displayed genes belong to this local TCS context.
Neighborhood span95 916-97 926 nt2 011 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
95 916 nt97 926 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EGL99_RS08855GCF_003862785#EGL99_RS08855
HKClassicCurrent focus
95 916-97 205 nt · Reverse (-)
EGL99_RS08860GCF_003862785#EGL99_RS08860
RROmpR
97 234-97 926 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_003862785#EGL99_RS08855The current gene is the representative for this cluster.
PFAM architectureHAMP + PAS + HisKA + HATPase_c4 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2182178
Simplified PFAM architecture for HKOC_2182178
PFAM domain coverage: 324 / 429 aa (75.5%)
1 aa429 aa
HAMPPASHisKAHATPase_c
- Simplified architecture: HAMP + PAS + HisKA + HATPase_c
- Raw architecture: HAMP[30-74] | PAS[87-193] | HisKA[202-267] | HATPase_c[317-422]
- Domain count: 4
- Matched identifier: HKOC_2182178
- Positioned domains: HAMP 30-74 ; PAS 87-193 ; HisKA 202-267 ; HATPase_c 317-422
Cluster members and taxonomy
Representative gene: GCF_003862785#EGL99_RS08855
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003862785
AssemblyASM386278v1 · Contighaploid
Genome composition4 086 452 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 99 · HK 47 · RR 52CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key