Gene detail

EGM03_RS11440

Histidine kinase, Classic

Clostridioides difficile · GCF_003862735

ClassHKTypeClassicLength311 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003862735#EGM03_RS11440Stable P2CS identifier used across views.
GenomeGCF_003862735Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2876519Run 6 · 160 sequences · id 100% · cov 80%
External referencesWP_022620538.1 · MIST4 EGM03_RS11440RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length311 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 311 aa (54.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Biotite-like domain view for EGM03_RS11440
Domain-by-domain annotation2 items
1 HisKA#1
94-156 aa · 63 aa · 20.3% of protein
Raw tokenHisKA:94:0.000000155:156:63:64
2 HATPase_c#2
204-310 aa · 107 aa · 34.4% of protein
Raw tokenHATPase_c:204:9.51e-31:310:107:109
  • Raw architecture: HisKA:94:0.000000155:156:63:64#HATPase_c:204:9.51e-31:310:107:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003862735::NZ_RRAM01000029.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span68540-70164Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGM03_11440RefSeq proteinWP_022620538.1
Context group IDGCF_003862735::NZ_RRAM01000029.1::G00039
Context members
EGM03_RS11435EGM03_RS11440
Partner locus tags
EGM03_RS11435EGM03_RS11440
Partner old locus tags
EGM03_11435EGM03_11440
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_022620538.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEGM03_RS11440Primary locus identifier stored in the genes table.
Old locus tagEGM03_11440Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RRAM01000029.1Sequence record reported by the local genomic context database.
Genomic interval69 229-70 164 nt936 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span68 540-70 164 ntGCF_003862735::NZ_RRAM01000029.1::G00039

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003862735::NZ_RRAM01000029.1::G00039

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RRAM01000029.1All displayed genes belong to this local TCS context.
Neighborhood span68 540-70 164 nt1 625 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
68 540 nt70 164 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EGM03_RS11435GCF_003862735#EGM03_RS11435
RROmpR

68 540-69 232 nt · Forward (+)

Old locus EGM03_11435RefSeq WP_009888625.1
EGM03_RS11440GCF_003862735#EGM03_RS11440
HKClassicCurrent focus

69 229-70 164 nt · Forward (+)

Old locus EGM03_11440RefSeq WP_022620538.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2876519Run 6 · HK · 160 sequences
Representative sequenceGCF_000448805#QKI_RS04550Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2876519

Simplified PFAM architecture for HKOC_2876519

PFAM domain coverage: 170 / 311 aa (54.7%)

1 aa311 aa
HisKA: 93-155 aaHisKAHATPase_c: 204-310 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[93-155] | HATPase_c[204-310]
  • Domain count: 2
  • Matched identifier: HKOC_2876519
  • Positioned domains: HisKA 93-155 ; HATPase_c 204-310
Cluster members and taxonomy
Visualization

Representative gene: GCF_000448805#QKI_RS04550

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003862735
AssemblyASM386273v1 · Contighaploid
Genome composition4 269 186 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 46 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key