1 HisKA#1
123-185 aa · 63 aa · 18.5% of protein
Raw token
HisKA:123:0.000000000271:185:63:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EGM10_RS12435
Histidine kinase, Classic
Clostridioides difficile · GCF_003862635
ClassHKTypeClassicLength341 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003862635#EGM10_RS12435Stable P2CS identifier used across views.
GenomeGCF_003862635Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length341 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage164 / 341 aa (48.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa341 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
237-337 aa · 101 aa · 29.6% of protein
Raw token
HATPase_c:237:5.62e-23:337:102:109- Raw architecture: HisKA:123:0.000000000271:185:63:64#HATPase_c:237:5.62e-23:337:102:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003862635::NZ_RRAT01000019.1::G00039
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span5402-7095Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGM10_12415RefSeq proteinWP_021378146.1
Context group ID
GCF_003862635::NZ_RRAT01000019.1::G00039Context members
EGM10_RS12435EGM10_RS12440
Partner locus tags
EGM10_RS12435EGM10_RS12440
Partner old locus tags
EGM10_12415EGM10_12420
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
No UniProt / GO / PubMed mapping was found for WP_021378146.1.
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEGM10_RS12435Primary locus identifier stored in the genes table.
Old locus tagEGM10_12415Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RRAT01000019.1Sequence record reported by the local genomic context database.
Genomic interval5 402-6 427 nt1 026 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span5 402-7 095 ntGCF_003862635::NZ_RRAT01000019.1::G00039
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003862635::NZ_RRAT01000019.1::G00039Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RRAT01000019.1All displayed genes belong to this local TCS context.
Neighborhood span5 402-7 095 nt1 694 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
5 402 nt7 095 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EGM10_RS12435GCF_003862635#EGM10_RS12435
HKClassicCurrent focus
5 402-6 427 nt · Reverse (-)
EGM10_RS12440GCF_003862635#EGM10_RS12440
RROmpR
6 430-7 095 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000451245#QE9_RS03190Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2834054
Simplified PFAM architecture for HKOC_2834054
PFAM domain coverage: 166 / 341 aa (48.7%)
1 aa341 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[122-185] | HATPase_c[236-337]
- Domain count: 2
- Matched identifier: HKOC_2834054
- Positioned domains: HisKA 122-185 ; HATPase_c 236-337
Cluster members and taxonomy
Representative gene: GCF_000451245#QE9_RS03190
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003862635
AssemblyASM386263v1 · Contighaploid
Genome composition4 045 057 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 102 · HK 49 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key