1 His_kinase#1
205-283 aa · 79 aa · 19.8% of protein
Raw token
His_kinase:205:2.78e-31:283:80:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EGM13_RS00615
Histidine kinase, Classic
Clostridioides difficile · GCF_003862595
ClassHKTypeClassicLength400 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003862595#EGM13_RS00615Stable P2CS identifier used across views.
GenomeGCF_003862595Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length400 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage180 / 400 aa (45.0%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
300-400 aa · 101 aa · 25.3% of protein
Raw token
HATPase_c:300:0.0000000015:400:108:109- Raw architecture: His_kinase:205:2.78e-31:283:80:80#HATPase_c:300:0.0000000015:400:108:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003862595::NZ_RRAW01000002.1::G00003
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span4114-6091Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGM13_00615RefSeq proteinWP_004454923.1
Context group ID
GCF_003862595::NZ_RRAW01000002.1::G00003Context members
EGM13_RS00615EGM13_RS00620
Partner locus tags
EGM13_RS00615EGM13_RS00620
Partner old locus tags
EGM13_00615EGM13_00620
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_004454923.1Primary protein accession used for annex mappings.
UniProt accessionQ182U1Primary UniProt accession resolved in the annex database.
UniProt IDQ182U1_CLOD6Display identifier provided by UniProt.
GO / PubMed4 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEGM13_RS00615Primary locus identifier stored in the genes table.
Old locus tagEGM13_00615Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RRAW01000002.1Sequence record reported by the local genomic context database.
Genomic interval4 114-5 316 nt1 203 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span4 114-6 091 ntGCF_003862595::NZ_RRAW01000002.1::G00003
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003862595::NZ_RRAW01000002.1::G00003Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RRAW01000002.1All displayed genes belong to this local TCS context.
Neighborhood span4 114-6 091 nt1 978 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
4 114 nt6 091 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EGM13_RS00615GCF_003862595#EGM13_RS00615
HKClassicCurrent focus
4 114-5 316 nt · Forward (+)
EGM13_RS00620GCF_003862595#EGM13_RS00620
RRLytTR
5 321-6 091 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS13950Use this link to inspect the representative gene detail.
PFAM architecture5TM-5TMR_LYT + His_kinase + HATPase_c3 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2440525
Simplified PFAM architecture for HKOC_2440525
PFAM domain coverage: 342 / 400 aa (85.5%)
1 aa400 aa
5TM-5TMR_LYTHis_kinaseHATPase_c
- Simplified architecture: 5TM-5TMR_LYT + His_kinase + HATPase_c
- Raw architecture: 5TM-5TMR_LYT[27-190] | His_kinase[205-281] | HATPase_c[299-399]
- Domain count: 3
- Matched identifier: HKOC_2440525
- Positioned domains: 5TM-5TMR_LYT 27-190 ; His_kinase 205-281 ; HATPase_c 299-399
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS13950
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003862595
AssemblyASM386259v1 · Contighaploid
Genome composition4 071 580 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 48 · RR 53CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key