1 His_kinase#1
305-376 aa · 72 aa · 14.4% of protein
Raw token
His_kinase:305:1.21e-24:376:72:80P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EGM15_RS02825
Histidine kinase, Classic
Clostridioides difficile · GCF_003862575
ClassHKTypeClassicLength501 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003862575#EGM15_RS02825Stable P2CS identifier used across views.
GenomeGCF_003862575Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
His_kinaseHATPase_c
Protein length501 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 501 aa (34.5%)Merged over positioned domains only.
Domain description1 His_kinase,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa501 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
396-496 aa · 101 aa · 20.2% of protein
Raw token
HATPase_c:396:0.00000286:496:107:109- Raw architecture: His_kinase:305:1.21e-24:376:72:80#HATPase_c:396:0.00000286:496:107:109
- Domain description: 1 His_kinase,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003862575::NZ_RRAY01000004.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span143-2460Genomic interval covered by the local TCS group.
Identifiers
Old locus tagEGM15_02825RefSeq proteinWP_011861709.1
Context group ID
GCF_003862575::NZ_RRAY01000004.1::G00011Context members
EGM15_RS02825EGM15_RS02830
Partner locus tags
EGM15_RS02825EGM15_RS02830
Partner old locus tags
EGM15_02825EGM15_02830
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_011861709.1Primary protein accession used for annex mappings.
UniProt accessionQ183S5Primary UniProt accession resolved in the annex database.
UniProt IDQ183S5_CLOD6Display identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
Reference hubs
GO terms
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEGM15_RS02825Primary locus identifier stored in the genes table.
Old locus tagEGM15_02825Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_RRAY01000004.1Sequence record reported by the local genomic context database.
Genomic interval143-1 648 nt1 506 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span143-2 460 ntGCF_003862575::NZ_RRAY01000004.1::G00011
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003862575::NZ_RRAY01000004.1::G00011Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_RRAY01000004.1All displayed genes belong to this local TCS context.
Neighborhood span143-2 460 nt2 318 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
143 nt2 460 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EGM15_RS02825GCF_003862575#EGM15_RS02825
HKClassicCurrent focus
143-1 648 nt · Forward (+)
EGM15_RS02830GCF_003862575#EGM15_RS02830
RRunclassified
1 762-2 460 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000009205#CD630_RS15165Use this link to inspect the representative gene detail.
PFAM architectureCupin_2 + His_kinase2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1468136
Simplified PFAM architecture for HKOC_1468136
PFAM domain coverage: 137 / 501 aa (27.3%)
1 aa501 aa
Cupin_2His_kinase
- Simplified architecture: Cupin_2 + His_kinase
- Raw architecture: Cupin_2[34-96] | His_kinase[303-376]
- Domain count: 2
- Matched identifier: HKOC_1468136
- Positioned domains: Cupin_2 34-96 ; His_kinase 303-376
Cluster members and taxonomy
Representative gene: GCF_000009205#CD630_RS15165
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003862575
AssemblyASM386257v1 · Contighaploid
Genome composition4 507 135 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 104 · HK 49 · RR 54CheA 1 · PP 1
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key