Gene detail

EBB60_RS09175

Response regulator NtrC family

Clostridioides difficile · GCF_003697205

ClassRRTypeNtrCLength440 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003697205#EBB60_RS09175Stable P2CS identifier used across views.
GenomeGCF_003697205Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterRROC_0333940Run 7 · 306 sequences · id 100% · cov 80%
External referencesWP_003423653.1 · D5Q520 · MIST4 EBB60_RS09175RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

Response_regAAA_5HTH_8
Protein length440 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage271 / 440 aa (61.6%)Merged over positioned domains only.
Domain description1 Response_reg,1 AAA_5,1 HTH_8Summary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa440 aa
Response_reg: 3-114 aa (112 aa)1AAA_5: 157-275 aa (119 aa)2HTH_8: 398-437 aa (40 aa)3
Domain-by-domain annotation3 items
1 Response_reg#1
3-114 aa · 112 aa · 25.5% of protein
Raw tokenResponse_reg:3:6.08e-27:114:112:111
2 AAA_5#2
157-275 aa · 119 aa · 27.0% of protein
Raw tokenAAA_5:157:0.0000000021:275:128:135
3 HTH_8#3
398-437 aa · 40 aa · 9.1% of protein
Raw tokenHTH_8:398:0.0000000000993:437:40:40
  • Raw architecture: Response_reg:3:6.08e-27:114:112:111#AAA_5:157:0.0000000021:275:128:135#HTH_8:398:0.0000000000993:437:40:40
  • Domain description: 1 Response_reg,1 AAA_5,1 HTH_8
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003697205::NZ_CP033213.1::G00025
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1887263-1890579Genomic interval covered by the local TCS group.
Context group IDGCF_003697205::NZ_CP033213.1::G00025
Context members
EBB60_RS09170EBB60_RS09175
Partner locus tags
EBB60_RS09170EBB60_RS09175
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_003423653.1Primary protein accession used for annex mappings.
UniProt accessionD5Q520Primary UniProt accession resolved in the annex database.
UniProt IDD5Q520_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagEBB60_RS09175Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CP033213.1Sequence record reported by the local genomic context database.
Genomic interval1 889 257-1 890 579 nt1 323 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span1 887 263-1 890 579 ntGCF_003697205::NZ_CP033213.1::G00025

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003697205::NZ_CP033213.1::G00025

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP033213.1All displayed genes belong to this local TCS context.
Neighborhood span1 887 263-1 890 579 nt3 317 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 887 263 nt1 890 579 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

EBB60_RS09170GCF_003697205#EBB60_RS09170
HKClassic

1 887 263-1 889 257 nt · Forward (+)

RefSeq WP_003423651.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterRROC_0333940Run 7 · RR · 306 sequences
Representative sequenceGCF_000164175#HMPREF0220_RS12755Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Sigma54_activat + AAA_lid_14 + HTH_84 domains in the representative PFAM annotation.

PFAM architecture for RROC_0333940

Simplified PFAM architecture for RROC_0333940

PFAM domain coverage: 386 / 440 aa (87.7%)

1 aa440 aa
Response_reg: 3-113 aaResponse_regResponse_reg: 3-113 aaResponse_regSigma54_activat: 137-300 aaSigma54_activatSigma54_activat: 137-300 aaSigma54_activatAAA_lid_14: 306-375 aaAAA_lid_14AAA_lid_14: 306-375 aaAAA_lid_14HTH_8: 397-437 aaHTH_8HTH_8: 397-437 aaHTH_8
Response_regSigma54_activatAAA_lid_14HTH_8
  • Simplified architecture: Response_reg + Sigma54_activat + AAA_lid_14 + HTH_8
  • Raw architecture: Response_reg[3-113] | Sigma54_activat[137-300] | AAA_lid_14[306-375] | HTH_8[397-437]
  • Domain count: 4
  • Matched identifier: RROC_0333940
  • Positioned domains: Response_reg 3-113 ; Response_reg 3-113 ; Sigma54_activat 137-300 ; Sigma54_activat 137-300 ; AAA_lid_14 306-375 ; AAA_lid_14 306-375 ; HTH_8 397-437 ; HTH_8 397-437
Cluster members and taxonomy
Visualization

Representative gene: GCF_000164175#HMPREF0220_RS12755

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003697205
AssemblyASM369720v1 · Complete Genomehaploid
Genome composition4 049 580 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 50 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key