1 HisKA#1
245-309 aa · 65 aa · 13.9% of protein
Raw token
HisKA:245:0.000000000000823:309:65:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EBB60_RS04045
Histidine kinase, Classic
Clostridioides difficile · GCF_003697205
ClassHKTypeClassicLength468 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003697205#EBB60_RS04045Stable P2CS identifier used across views.
GenomeGCF_003697205Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length468 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage174 / 468 aa (37.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa468 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
357-465 aa · 109 aa · 23.3% of protein
Raw token
HATPase_c:357:1.94e-18:465:110:109- Raw architecture: HisKA:245:0.000000000000823:309:65:64#HATPase_c:357:1.94e-18:465:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003697205::NZ_CP033213.1::G00011
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span782832-784996Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_003697205::NZ_CP033213.1::G00011Context members
EBB60_RS04040EBB60_RS04045
Partner locus tags
EBB60_RS04040EBB60_RS04045
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003418198.1Primary protein accession used for annex mappings.
UniProt accessionD5Q0Q3Primary UniProt accession resolved in the annex database.
UniProt IDD5Q0Q3_CLODIDisplay identifier provided by UniProt.
GO / PubMed1 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEBB60_RS04045Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CP033213.1Sequence record reported by the local genomic context database.
Genomic interval783 590-784 996 nt1 407 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span782 832-784 996 ntGCF_003697205::NZ_CP033213.1::G00011
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003697205::NZ_CP033213.1::G00011Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP033213.1All displayed genes belong to this local TCS context.
Neighborhood span782 832-784 996 nt2 165 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
782 832 nt784 996 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
EBB60_RS04040GCF_003697205#EBB60_RS04040
RROmpR
782 832-783 545 nt · Forward (+)
EBB60_RS04045GCF_003697205#EBB60_RS04045
HKClassicCurrent focus
783 590-784 996 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000155065#QAE_RS0203390Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_1737648
Simplified PFAM architecture for HKOC_1737648
PFAM domain coverage: 175 / 468 aa (37.4%)
1 aa468 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[245-310] | HATPase_c[358-466]
- Domain count: 2
- Matched identifier: HKOC_1737648
- Positioned domains: HisKA 245-310 ; HATPase_c 358-466
Cluster members and taxonomy
Representative gene: GCF_000155065#QAE_RS0203390
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003697205
AssemblyASM369720v1 · Complete Genomehaploid
Genome composition4 049 580 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 50 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key