1 Hpt#1
3-106 aa · 104 aa · 14.9% of protein
Raw token
Hpt:3:0.00000000000000647:106:104:84P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
EBB60_RS03400
Histidine kinase, CheA
Clostridioides difficile · GCF_003697205
ClassHKTypeCheALength700 aaTM0ValidatedNoCompleteYesContextorphan
Gene IDGCF_003697205#EBB60_RS03400Stable P2CS identifier used across views.
GenomeGCF_003697205Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HptH-kinase_dimHATPase_cCheW
Protein length700 aaLength used to scale native and Biotite-like views.
Annotated domains44 with usable coordinates.
Domain coverage440 / 700 aa (62.9%)Merged over positioned domains only.
Domain description1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheWSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa700 aa
Domain-by-domain annotation4 items
2 H-kinase_dim#2
312-373 aa · 62 aa · 8.9% of protein
Raw token
H-kinase_dim:312:0.00000000000000566:373:67:673 HATPase_c#3
421-559 aa · 139 aa · 19.9% of protein
Raw token
HATPase_c:421:4.54e-18:559:139:1094 CheW#4
564-698 aa · 135 aa · 19.3% of protein
Raw token
CheW:564:2.77e-22:698:136:138- Raw architecture: Hpt:3:0.00000000000000647:106:104:84#H-kinase_dim:312:0.00000000000000566:373:67:67#HATPase_c:421:4.54e-18:559:139:109#CheW:564:2.77e-22:698:136:138
- Domain description: 1 Hpt,1 H-kinase_dim,1 HATPase_c,1 CheW
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelorphanGCF_003697205::NZ_CP033213.1::G00010
Group size11 locus tag listed below.
HK / RR1 / 0Counts resolved for the local TCS neighborhood.
Context span636610-638712Genomic interval covered by the local TCS group.
Identifiers
Context group ID
GCF_003697205::NZ_CP033213.1::G00010Context members
EBB60_RS03400
Partner locus tags
EBB60_RS03400
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_003417904.1Primary protein accession used for annex mappings.
UniProt accessionD5Q0C8Primary UniProt accession resolved in the annex database.
UniProt IDD5Q0C8_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagEBB60_RS03400Primary locus identifier stored in the genes table.
Old locus tagUnavailableNo previous locus tag available for this gene.
Contig / repliconNZ_CP033213.1Sequence record reported by the local genomic context database.
Genomic interval636 610-638 712 nt2 103 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span636 610-638 712 ntGCF_003697205::NZ_CP033213.1::G00010
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003697205::NZ_CP033213.1::G00010Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelorphanNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP033213.1All displayed genes belong to this local TCS context.
Neighborhood span636 610-638 712 nt2 103 nt
Members11 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
636 610 nt638 712 nt
Neighborhood gene cards
1 gene in the current local neighborhood.
EBB60_RS03400GCF_003697205#EBB60_RS03400
HKCheACurrent focus
636 610-638 712 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000164175#HMPREF0220_RS08600Use this link to inspect the representative gene detail.
PFAM architectureHpt + P2 + H-kinase_dim + HATPase_c + CheW5 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0768948
Simplified PFAM architecture for HKOC_0768948
PFAM domain coverage: 513 / 700 aa (73.3%)
1 aa700 aa
HptP2H-kinase_dimHATPase_cCheW
- Simplified architecture: Hpt + P2 + H-kinase_dim + HATPase_c + CheW
- Raw architecture: Hpt[3-104] | P2[164-240] | H-kinase_dim[312-373] | HATPase_c[422-559] | CheW[565-698]
- Domain count: 5
- Matched identifier: HKOC_0768948
- Positioned domains: Hpt 3-104 ; P2 164-240 ; H-kinase_dim 312-373 ; HATPase_c 422-559 ; CheW 565-698
Cluster members and taxonomy
Representative gene: GCF_000164175#HMPREF0220_RS08600
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003697205
AssemblyASM369720v1 · Complete Genomehaploid
Genome composition4 049 580 bp · 28,5% GCClostridioides difficile
Signal transduction countsGenes 101 · HK 50 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key