1 HisKA#1
168-234 aa · 67 aa · 17.0% of protein
Raw token
HisKA:168:0.000000000000741:234:67:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C0215_RS17455
Histidine kinase, Classic
Clostridioides difficile · GCF_003625415
ClassHKTypeClassicLength393 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003625415#C0215_RS17455Stable P2CS identifier used across views.
GenomeGCF_003625415Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length393 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage176 / 393 aa (44.8%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa393 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
280-388 aa · 109 aa · 27.7% of protein
Raw token
HATPase_c:280:1.27e-26:388:110:109- Raw architecture: HisKA:168:0.000000000000741:234:67:64#HATPase_c:280:1.27e-26:388:110:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003625415::NZ_PNER01000024.1::G00023
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span41503-43366Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC0215_17440RefSeq proteinWP_009894075.1
Context group ID
GCF_003625415::NZ_PNER01000024.1::G00023Context members
C0215_RS17450C0215_RS17455
Partner locus tags
C0215_RS17450C0215_RS17455
Partner old locus tags
C0215_17435C0215_17440
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009894075.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R7M5Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R7M5_CLODIDisplay identifier provided by UniProt.
GO / PubMed3 / 0Unique GO terms and literature references available below.
Reference hubs
GO terms
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC0215_RS17455Primary locus identifier stored in the genes table.
Old locus tagC0215_17440Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PNER01000024.1Sequence record reported by the local genomic context database.
Genomic interval42 185-43 366 nt1 182 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span41 503-43 366 ntGCF_003625415::NZ_PNER01000024.1::G00023
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003625415::NZ_PNER01000024.1::G00023Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PNER01000024.1All displayed genes belong to this local TCS context.
Neighborhood span41 503-43 366 nt1 864 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
41 503 nt43 366 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
C0215_RS17450GCF_003625415#C0215_RS17450
RROmpR
41 503-42 195 nt · Forward (+)
C0215_RS17455GCF_003625415#C0215_RS17455
HKClassicCurrent focus
42 185-43 366 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0218365Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2503238
Simplified PFAM architecture for HKOC_2503238
PFAM domain coverage: 175 / 393 aa (44.5%)
1 aa393 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[168-233] | HATPase_c[281-389]
- Domain count: 2
- Matched identifier: HKOC_2503238
- Positioned domains: HisKA 168-233 ; HATPase_c 281-389
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0218365
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003625415
AssemblyASM362541v1 · Contighaploid
Genome composition4 190 005 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key