1 HisKA#1
135-198 aa · 64 aa · 17.8% of protein
Raw token
HisKA:135:0.000000000000365:198:64:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
C0215_RS04070
Histidine kinase, Classic
Clostridioides difficile · GCF_003625415
ClassHKTypeClassicLength360 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003625415#C0215_RS04070Stable P2CS identifier used across views.
GenomeGCF_003625415Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length360 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage161 / 360 aa (44.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
248-344 aa · 97 aa · 26.9% of protein
Raw token
HATPase_c:248:2.05e-21:344:97:109- Raw architecture: HisKA:135:0.000000000000365:198:64:64#HATPase_c:248:2.05e-21:344:97:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003625415::NZ_PNER01000003.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span61718-63551Genomic interval covered by the local TCS group.
Identifiers
Old locus tagC0215_04065RefSeq proteinWP_012816161.1
Context group ID
GCF_003625415::NZ_PNER01000003.1::G00038Context members
C0215_RS04065C0215_RS04070
Partner locus tags
C0215_RS04065C0215_RS04070
Partner old locus tags
C0215_04060C0215_04065
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_012816161.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3N707Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3N707_CLODCDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagC0215_RS04070Primary locus identifier stored in the genes table.
Old locus tagC0215_04065Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_PNER01000003.1Sequence record reported by the local genomic context database.
Genomic interval62 469-63 551 nt1 083 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span61 718-63 551 ntGCF_003625415::NZ_PNER01000003.1::G00038
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003625415::NZ_PNER01000003.1::G00038Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_PNER01000003.1All displayed genes belong to this local TCS context.
Neighborhood span61 718-63 551 nt1 834 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
61 718 nt63 551 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
C0215_RS04065GCF_003625415#C0215_RS04065
RROmpR
61 718-62 419 nt · Forward (+)
C0215_RS04070GCF_003625415#C0215_RS04070
HKClassicCurrent focus
62 469-63 551 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0208405Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2746944
Simplified PFAM architecture for HKOC_2746944
PFAM domain coverage: 161 / 360 aa (44.7%)
1 aa360 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[136-198] | HATPase_c[248-345]
- Domain count: 2
- Matched identifier: HKOC_2746944
- Positioned domains: HisKA 136-198 ; HATPase_c 248-345
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0208405
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003625415
AssemblyASM362541v1 · Contighaploid
Genome composition4 190 005 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key