1 HisKA#1
124-189 aa · 66 aa · 19.2% of protein
Raw token
HisKA:124:0.000000414:189:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA422_RS10065
Histidine kinase, Classic
Clostridioides difficile · GCF_003597895
ClassHKTypeClassicLength343 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003597895#DA422_RS10065Stable P2CS identifier used across views.
GenomeGCF_003597895Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length343 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage167 / 343 aa (48.7%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa343 aa
Domain-by-domain annotation2 items
2 HATPase_c#2
241-341 aa · 101 aa · 29.4% of protein
Raw token
HATPase_c:241:2.84e-24:341:101:109- Raw architecture: HisKA:124:0.000000414:189:66:64#HATPase_c:241:2.84e-24:341:101:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003597895::NZ_CP028525.1::G00034
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2085611-2087318Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA422_10065RefSeq proteinWP_009893355.1
Context group ID
GCF_003597895::NZ_CP028525.1::G00034Context members
DA422_RS10060DA422_RS10065
Partner locus tags
DA422_RS10060DA422_RS10065
Partner old locus tags
DA422_10060DA422_10065
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009893355.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QZ17Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QZ17_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA422_RS10065Primary locus identifier stored in the genes table.
Old locus tagDA422_10065Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP028525.1Sequence record reported by the local genomic context database.
Genomic interval2 086 287-2 087 318 nt1 032 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span2 085 611-2 087 318 ntGCF_003597895::NZ_CP028525.1::G00034
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003597895::NZ_CP028525.1::G00034Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP028525.1All displayed genes belong to this local TCS context.
Neighborhood span2 085 611-2 087 318 nt1 708 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 085 611 nt2 087 318 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DA422_RS10060GCF_003597895#DA422_RS10060
RROmpR
2 085 611-2 086 297 nt · Forward (+)
DA422_RS10065GCF_003597895#DA422_RS10065
HKClassicCurrent focus
2 086 287-2 087 318 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0209905Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2827738
Simplified PFAM architecture for HKOC_2827738
PFAM domain coverage: 173 / 343 aa (50.4%)
1 aa343 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[124-189] | HATPase_c[236-342]
- Domain count: 2
- Matched identifier: HKOC_2827738
- Positioned domains: HisKA 124-189 ; HATPase_c 236-342
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0209905
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003597895
AssemblyASM359789v1 · Chromosomehaploid
Genome composition4 182 371 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key