Gene detail

DA422_RS06435

Histidine kinase, Classic

Clostridioides difficile · GCF_003597895

ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003597895#DA422_RS06435Stable P2CS identifier used across views.
GenomeGCF_003597895Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2557601Run 6 · 352 sequences · id 100% · cov 80%
External referencesWP_009889050.1 · A0AB74QZK6 · MIST4 DA422_RS06435RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKA_3HATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage149 / 386 aa (38.6%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa386 aa
HisKA_3: 187-250 aa (64 aa)1HATPase_c: 293-377 aa (85 aa)2
Domain-by-domain annotation2 items
1 HisKA_3#1
187-250 aa · 64 aa · 16.6% of protein
Raw tokenHisKA_3:187:9.36e-20:250:65:68
2 HATPase_c#2
293-377 aa · 85 aa · 22.0% of protein
Raw tokenHATPase_c:293:0.00000000000129:377:104:109
  • Raw architecture: HisKA_3:187:9.36e-20:250:65:68#HATPase_c:293:0.00000000000129:377:104:109
  • Domain description: 1 HisKA_3,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003597895::NZ_CP028525.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1329122-1330919Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA422_06440RefSeq proteinWP_009889050.1
Context group IDGCF_003597895::NZ_CP028525.1::G00020
Context members
DA422_RS06430DA422_RS06435
Partner locus tags
DA422_RS06430DA422_RS06435
Partner old locus tags
DA422_06435DA422_06440
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009889050.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QZK6Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QZK6_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA422_RS06435Primary locus identifier stored in the genes table.
Old locus tagDA422_06440Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP028525.1Sequence record reported by the local genomic context database.
Genomic interval1 329 759-1 330 919 nt1 161 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 329 122-1 330 919 ntGCF_003597895::NZ_CP028525.1::G00020

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003597895::NZ_CP028525.1::G00020

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP028525.1All displayed genes belong to this local TCS context.
Neighborhood span1 329 122-1 330 919 nt1 798 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 329 122 nt1 330 919 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DA422_RS06430GCF_003597895#DA422_RS06430
RRNarL

1 329 122-1 329 766 nt · Reverse (-)

Old locus DA422_06435RefSeq WP_009889048.1
DA422_RS06435GCF_003597895#DA422_RS06435
HKClassicCurrent focus

1 329 759-1 330 919 nt · Reverse (-)

Old locus DA422_06440RefSeq WP_009889050.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2557601Run 6 · HK · 352 sequences
Representative sequenceGCF_000003215#QAC_RS0206170Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2557601

Simplified PFAM architecture for HKOC_2557601

PFAM domain coverage: 149 / 386 aa (38.6%)

1 aa386 aa
HisKA_3: 187-250 aaHisKA_3HATPase_c: 293-377 aaHATPase_c
HisKA_3HATPase_c
  • Simplified architecture: HisKA_3 + HATPase_c
  • Raw architecture: HisKA_3[187-250] | HATPase_c[293-377]
  • Domain count: 2
  • Matched identifier: HKOC_2557601
  • Positioned domains: HisKA_3 187-250 ; HATPase_c 293-377
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0206170

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 352 total members. Page 1 / 8.

GCF_000003215#QAC_RS0206170 (representative)
QAC_RS0206170 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000027105#CDR20291_RS06175
CDR20291_RS06175 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000085225#CD196_RS06320
CD196_RS06320 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000154645#UAA_RS0208040
UAA_RS0208040 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000154665#QAD_RS0206355
QAD_RS0206355 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000154685#AEC_RS0207640
AEC_RS0207640 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000155045#EAA_RS0206070
EAA_RS0206070 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000210455#CD7855_RS06165
CD7855_RS06165 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000211235#CDBI1_RS06260
CDBI1_RS06260 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000450145#QK3_RS06665
QK3_RS06665 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000450765#QO5_RS06945
QO5_RS06945 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000451065#QSC_RS05990
QSC_RS05990 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000451785#QSO_RS11120
QSO_RS11120 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000451885#QU5_RS06040
QU5_RS06040 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000452005#QUI_RS12305
QUI_RS12305 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000530295#BN174_RS06190
BN174_RS06190 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000531255#BN173_RS06090
BN173_RS06090 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000531785#BN176_RS06285
BN176_RS06285 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_000826625#BN2378_RS14780
BN2378_RS14780 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_001484885#CD26A54R_RS06135
CD26A54R_RS06135 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_001484895#CD26A54S_RS06215
CD26A54S_RS06215 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_001857645#HMPREF3082_RS17865
HMPREF3082_RS17865 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_001971835#BER28_RS06540
BER28_RS06540 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_001972015#BER29_RS06485
BER29_RS06485 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002301945#BGU80_RS07345
BGU80_RS07345 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002302765#BGV01_RS01645
BGV01_RS01645 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002303165#BGV24_RS08955
BGV24_RS08955 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002335485#NCKUH21_RS05940
NCKUH21_RS05940 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002812585#CWR57_RS05870
CWR57_RS05870 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002891495#AMR93_RS01175
AMR93_RS01175 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002891625#AMR90_RS03070
AMR90_RS03070 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002945415#C3W74_RS06545
C3W74_RS06545 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002945515#C3L34_RS06530
C3L34_RS06530 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002945665#C3347_RS06550
C3347_RS06550 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002945755#C3348_RS06550
C3348_RS06550 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002945855#C3350_RS06560
C3350_RS06560 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002945945#C3349_RS06550
C3349_RS06550 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002946135#C3352_RS06560
C3352_RS06560 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002946195#C3353_RS06550
C3353_RS06550 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_002954285#AMR92_RS04180
AMR92_RS04180 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_003313545#CDIF27638_RS06540
CDIF27638_RS06540 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_003313585#CDIF27640_RS06530
CDIF27640_RS06530 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_003482035#CDIF28196_RS06530
CDIF28196_RS06530 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_003597795#DA426_RS13375
DA426_RS13375 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_003597815#DA430_RS06535
DA430_RS06535 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_003597835#DA432_RS06490
DA432_RS06490 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_003597895#DA422_RS06435
DA422_RS06435 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_003597915#DA436_RS06485
DA436_RS06485 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_003625415#C0215_RS06375
C0215_RS06375 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6
GCF_003625425#C0983_RS01065
C0983_RS01065 · HK · Classic
RefSeq: WP_009889050.1
UniProt: A0AB74QZK6

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003597895
AssemblyASM359789v1 · Chromosomehaploid
Genome composition4 182 371 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key