Gene detail

DA418_RS09355

Histidine kinase, Classic

Clostridioides difficile · GCF_003597875

ClassHKTypeClassicLength239 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003597875#DA418_RS09355Stable P2CS identifier used across views.
GenomeGCF_003597875Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2883601Run 6 · 969 sequences · id 100% · cov 80%
External referencesWP_021399326.1 · MIST4 DA418_RS09355RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length239 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage163 / 239 aa (68.2%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa239 aa
HisKA: 19-81 aa (63 aa)1HATPase_c: 133-232 aa (100 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
19-81 aa · 63 aa · 26.4% of protein
Raw tokenHisKA:19:0.0000000725:81:63:64
2 HATPase_c#2
133-232 aa · 100 aa · 41.8% of protein
Raw tokenHATPase_c:133:6.51e-23:232:100:109
  • Raw architecture: HisKA:19:0.0000000725:81:63:64#HATPase_c:133:6.51e-23:232:100:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003597875::NZ_CP028524.1::G00034
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1983016-1984596Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA418_09365RefSeq proteinWP_021399326.1
Context group IDGCF_003597875::NZ_CP028524.1::G00034
Context members
DA418_RS09355DA418_RS09360
Partner locus tags
DA418_RS09355DA418_RS09360
Partner old locus tags
DA418_09365DA418_09370
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_021399326.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA418_RS09355Primary locus identifier stored in the genes table.
Old locus tagDA418_09365Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP028524.1Sequence record reported by the local genomic context database.
Genomic interval1 983 016-1 983 735 nt720 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 983 016-1 984 596 ntGCF_003597875::NZ_CP028524.1::G00034

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003597875::NZ_CP028524.1::G00034

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP028524.1All displayed genes belong to this local TCS context.
Neighborhood span1 983 016-1 984 596 nt1 581 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 983 016 nt1 984 596 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DA418_RS09355GCF_003597875#DA418_RS09355
HKClassicCurrent focus

1 983 016-1 983 735 nt · Reverse (-)

Old locus DA418_09365RefSeq WP_021399326.1
DA418_RS09360GCF_003597875#DA418_RS09360
RROmpR

1 983 925-1 984 596 nt · Reverse (-)

Old locus DA418_09370RefSeq WP_009897090.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2883601Run 6 · HK · 969 sequences
Representative sequenceGCF_033840375#SIK50_RS12330Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2883601

Simplified PFAM architecture for HKOC_2883601

PFAM domain coverage: 165 / 304 aa (54.3%)

1 aa304 aa
HisKA: 84-146 aaHisKAHATPase_c: 197-298 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[84-146] | HATPase_c[197-298]
  • Domain count: 2
  • Matched identifier: HKOC_2883601
  • Positioned domains: HisKA 84-146 ; HATPase_c 197-298
Cluster members and taxonomy
Visualization

Representative gene: GCF_033840375#SIK50_RS12330

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003597875
AssemblyASM359787v1 · Chromosomehaploid
Genome composition4 144 005 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 97 · HK 46 · RR 51CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key