1 HisKA_3#1
187-250 aa · 64 aa · 16.6% of protein
Raw token
HisKA_3:187:9.36e-20:250:65:68P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA432_RS06490
Histidine kinase, Classic
Clostridioides difficile · GCF_003597835
ClassHKTypeClassicLength386 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003597835#DA432_RS06490Stable P2CS identifier used across views.
GenomeGCF_003597835Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKA_3HATPase_c
Protein length386 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage149 / 386 aa (38.6%)Merged over positioned domains only.
Domain description1 HisKA_3,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
293-377 aa · 85 aa · 22.0% of protein
Raw token
HATPase_c:293:0.00000000000129:377:104:109- Raw architecture: HisKA_3:187:9.36e-20:250:65:68#HATPase_c:293:0.00000000000129:377:104:109
- Domain description: 1 HisKA_3,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003597835::NZ_CP028528.1::G00020
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span1334300-1336097Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA432_06500RefSeq proteinWP_009889050.1
Context group ID
GCF_003597835::NZ_CP028528.1::G00020Context members
DA432_RS06485DA432_RS06490
Partner locus tags
DA432_RS06485DA432_RS06490
Partner old locus tags
DA432_06495DA432_06500
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009889050.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74QZK6Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74QZK6_CLODIDisplay identifier provided by UniProt.
GO / PubMed4 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA432_RS06490Primary locus identifier stored in the genes table.
Old locus tagDA432_06500Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP028528.1Sequence record reported by the local genomic context database.
Genomic interval1 334 937-1 336 097 nt1 161 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span1 334 300-1 336 097 ntGCF_003597835::NZ_CP028528.1::G00020
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003597835::NZ_CP028528.1::G00020Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP028528.1All displayed genes belong to this local TCS context.
Neighborhood span1 334 300-1 336 097 nt1 798 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
1 334 300 nt1 336 097 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DA432_RS06485GCF_003597835#DA432_RS06485
RRNarL
1 334 300-1 334 944 nt · Reverse (-)
DA432_RS06490GCF_003597835#DA432_RS06490
HKClassicCurrent focus
1 334 937-1 336 097 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0206170Use this link to inspect the representative gene detail.
PFAM architectureHisKA_3 + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_2557601
Simplified PFAM architecture for HKOC_2557601
PFAM domain coverage: 149 / 386 aa (38.6%)
1 aa386 aa
HisKA_3HATPase_c
- Simplified architecture: HisKA_3 + HATPase_c
- Raw architecture: HisKA_3[187-250] | HATPase_c[293-377]
- Domain count: 2
- Matched identifier: HKOC_2557601
- Positioned domains: HisKA_3 187-250 ; HATPase_c 293-377
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0206170
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003597835
AssemblyASM359783v1 · Chromosomehaploid
Genome composition4 119 431 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 103 · HK 49 · RR 54CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key