1 Response_reg#1
5-113 aa · 109 aa · 46.6% of protein
Raw token
Response_reg:5:1.56e-29:113:110:111P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA426_RS12350
Response regulator OmpR family
Clostridioides difficile · GCF_003597795
ClassRRTypeOmpRLength234 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003597795#DA426_RS12350Stable P2CS identifier used across views.
GenomeGCF_003597795Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
Response_regTrans_reg_C
Protein length234 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage187 / 234 aa (79.9%)Merged over positioned domains only.
Domain description1 Response_reg,1 Trans_reg_CSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 Trans_reg_C#2
148-225 aa · 78 aa · 33.3% of protein
Raw token
Trans_reg_C:148:1.54e-30:225:78:77- Raw architecture: Response_reg:5:1.56e-29:113:110:111#Trans_reg_C:148:1.54e-30:225:78:77
- Domain description: 1 Response_reg,1 Trans_reg_C
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpairedGCF_003597795::NZ_CP028526.1::G00038
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span2673741-2675676Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA426_12345RefSeq proteinWP_009899785.1
Context group ID
GCF_003597795::NZ_CP028526.1::G00038Context members
DA426_RS12345DA426_RS12350
Partner locus tags
DA426_RS12345DA426_RS12350
Partner old locus tags
DA426_12340DA426_12345
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009899785.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R0U4Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R0U4_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.
Reference hubs
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA426_RS12350Primary locus identifier stored in the genes table.
Old locus tagDA426_12345Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP028526.1Sequence record reported by the local genomic context database.
Genomic interval2 674 972-2 675 676 nt705 nt · Reverse (-)
StrandReverse (-)Strand sign follows the local context database convention.
Local TCS group span2 673 741-2 675 676 ntGCF_003597795::NZ_CP028526.1::G00038
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003597795::NZ_CP028526.1::G00038Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP028526.1All displayed genes belong to this local TCS context.
Neighborhood span2 673 741-2 675 676 nt1 936 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
2 673 741 nt2 675 676 nt
Neighborhood gene cards
2 genes in the current local neighborhood.
DA426_RS12345GCF_003597795#DA426_RS12345
HKClassic
2 673 741-2 674 994 nt · Reverse (-)
DA426_RS12350GCF_003597795#DA426_RS12350
RROmpRCurrent focus
2 674 972-2 675 676 nt · Reverse (-)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000027105#CDR20291_RS07180Use this link to inspect the representative gene detail.
PFAM architectureResponse_reg + Trans_reg_C2 domains in the representative PFAM annotation.
PFAM architecture for RROC_0862707
Simplified PFAM architecture for RROC_0862707
PFAM domain coverage: 185 / 241 aa (76.8%)
1 aa241 aa
Response_regTrans_reg_C
- Simplified architecture: Response_reg + Trans_reg_C
- Raw architecture: Response_reg[12-120] | Trans_reg_C[156-231]
- Domain count: 2
- Matched identifier: RROC_0862707
- Positioned domains: Response_reg 12-120 ; Response_reg 12-120 ; Trans_reg_C 156-231 ; Trans_reg_C 156-231
Cluster members and taxonomy
Representative gene: GCF_000027105#CDR20291_RS07180
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003597795
AssemblyASM359779v1 · Chromosomehaploid
Genome composition4 221 948 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key