Gene detail

DA426_RS04445

Histidine kinase, Classic

Clostridioides difficile · GCF_003597795

ClassHKTypeClassicLength257 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003597795#DA426_RS04445Stable P2CS identifier used across views.
GenomeGCF_003597795Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2916032Run 6 · 365 sequences · id 100% · cov 80%
External referencesWP_330360517.1 · MIST4 DA426_RS04445RefSeq · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length257 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage157 / 257 aa (61.1%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa257 aa
HisKA: 46-93 aa (48 aa)1HATPase_c: 139-247 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
46-93 aa · 48 aa · 18.7% of protein
Raw tokenHisKA:46:0.000000764:93:53:64
2 HATPase_c#2
139-247 aa · 109 aa · 42.4% of protein
Raw tokenHATPase_c:139:4.15e-23:247:109:109
  • Raw architecture: HisKA:46:0.000000764:93:53:64#HATPase_c:139:4.15e-23:247:109:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003597795::NZ_CP028526.1::G00012
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span941764-943470Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA426_04440RefSeq proteinWP_330360517.1
Context group IDGCF_003597795::NZ_CP028526.1::G00012
Context members
DA426_RS04440DA426_RS04445
Partner locus tags
DA426_RS04440DA426_RS04445
Partner old locus tags
DA426_04435DA426_04440
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

No UniProt / GO / PubMed mapping was found for WP_330360517.1.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA426_RS04445Primary locus identifier stored in the genes table.
Old locus tagDA426_04440Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP028526.1Sequence record reported by the local genomic context database.
Genomic interval942 697-943 470 nt774 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span941 764-943 470 ntGCF_003597795::NZ_CP028526.1::G00012

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003597795::NZ_CP028526.1::G00012

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP028526.1All displayed genes belong to this local TCS context.
Neighborhood span941 764-943 470 nt1 707 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
941 764 nt943 470 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DA426_RS04440GCF_003597795#DA426_RS04440
RROmpR

941 764-942 456 nt · Forward (+)

Old locus DA426_04435RefSeq WP_003429090.1
DA426_RS04445GCF_003597795#DA426_RS04445
HKClassicCurrent focus

942 697-943 470 nt · Forward (+)

Old locus DA426_04440RefSeq WP_330360517.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2916032Run 6 · HK · 365 sequences
Representative sequenceGCF_000003215#QAC_RS0214845Use this link to inspect the representative gene detail.
PFAM architectureHATPase_c1 domain in the representative PFAM annotation.

PFAM architecture for HKOC_2916032

Simplified PFAM architecture for HKOC_2916032

PFAM domain coverage: 109 / 257 aa (42.4%)

1 aa257 aa
HATPase_c: 140-248 aaHATPase_c
HATPase_c
  • Simplified architecture: HATPase_c
  • Raw architecture: HATPase_c[140-248]
  • Domain count: 1
  • Matched identifier: HKOC_2916032
  • Positioned domains: HATPase_c 140-248
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0214845

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003597795
AssemblyASM359779v1 · Chromosomehaploid
Genome composition4 221 948 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key