Gene detail

DA426_RS02885

Histidine kinase, Classic

Clostridioides difficile · GCF_003597795

ClassHKTypeClassicLength376 aaTM0ValidatedNoCompleteYesContextpaired
Gene IDGCF_003597795#DA426_RS02885Stable P2CS identifier used across views.
GenomeGCF_003597795Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2641393Run 6 · 369 sequences · id 100% · cov 80%
External referencesWP_009891645.1 · A0A0H3NB30 · MIST4 DA426_RS02885RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HAMPHisKAHATPase_c
Protein length376 aaLength used to scale native and Biotite-like views.
Annotated domains33 with usable coordinates.
Domain coverage246 / 376 aa (65.4%)Merged over positioned domains only.
Domain description1 HAMP,1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa376 aa
HAMP: 62-131 aa (70 aa)1HisKA: 156-221 aa (66 aa)2HATPase_c: 267-376 aa (110 aa)3
Domain-by-domain annotation3 items
1 HAMP#1
62-131 aa · 70 aa · 18.6% of protein
Raw tokenHAMP:62:0.0000000000132:131:70:69
2 HisKA#2
156-221 aa · 66 aa · 17.6% of protein
Raw tokenHisKA:156:0.00000000000000561:221:66:64
3 HATPase_c#3
267-376 aa · 110 aa · 29.3% of protein
Raw tokenHATPase_c:267:9.54e-17:376:111:109
  • Raw architecture: HAMP:62:0.0000000000132:131:70:69#HisKA:156:0.00000000000000561:221:66:64#HATPase_c:267:9.54e-17:376:111:109
  • Domain description: 1 HAMP,1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpairedGCF_003597795::NZ_CP028526.1::G00009
Group size22 locus tags listed below.
HK / RR1 / 1Counts resolved for the local TCS neighborhood.
Context span591339-593137Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA426_02885RefSeq proteinWP_009891645.1
Context group IDGCF_003597795::NZ_CP028526.1::G00009
Context members
DA426_RS02880DA426_RS02885
Partner locus tags
DA426_RS02880DA426_RS02885
Partner old locus tags
DA426_02880DA426_02885
Partner protein IDs

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009891645.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3NB30Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3NB30_CLODCDisplay identifier provided by UniProt.
GO / PubMed3 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA426_RS02885Primary locus identifier stored in the genes table.
Old locus tagDA426_02885Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP028526.1Sequence record reported by the local genomic context database.
Genomic interval592 007-593 137 nt1 131 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span591 339-593 137 ntGCF_003597795::NZ_CP028526.1::G00009

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003597795::NZ_CP028526.1::G00009

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpairedNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP028526.1All displayed genes belong to this local TCS context.
Neighborhood span591 339-593 137 nt1 799 nt
Members21 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
591 339 nt593 137 nt
Neighborhood gene cards

2 genes in the current local neighborhood.

DA426_RS02880GCF_003597795#DA426_RS02880
RROmpR

591 339-592 010 nt · Forward (+)

Old locus DA426_02880RefSeq WP_009891647.1
DA426_RS02885GCF_003597795#DA426_RS02885
HKClassicCurrent focus

592 007-593 137 nt · Forward (+)

Old locus DA426_02885RefSeq WP_009891645.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2641393Run 6 · HK · 369 sequences
Representative sequenceGCF_000003215#QAC_RS0216165Use this link to inspect the representative gene detail.
PFAM architectureHAMP + HisKA + HATPase_c3 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2641393

Simplified PFAM architecture for HKOC_2641393

PFAM domain coverage: 227 / 376 aa (60.4%)

1 aa376 aa
HAMP: 79-131 aaHAMPHisKA: 156-221 aaHisKAHATPase_c: 268-375 aaHATPase_c
HAMPHisKAHATPase_c
  • Simplified architecture: HAMP + HisKA + HATPase_c
  • Raw architecture: HAMP[79-131] | HisKA[156-221] | HATPase_c[268-375]
  • Domain count: 3
  • Matched identifier: HKOC_2641393
  • Positioned domains: HAMP 79-131 ; HisKA 156-221 ; HATPase_c 268-375
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0216165

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 369 total members. Page 1 / 8.

GCF_000003215#QAC_RS0216165 (representative)
QAC_RS0216165 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000027105#CDR20291_RS16505
CDR20291_RS16505 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000085225#CD196_RS16230
CD196_RS16230 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000154645#UAA_RS0218065
UAA_RS0218065 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000154665#QAD_RS0216260
QAD_RS0216260 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000154685#AEC_RS0217625
AEC_RS0217625 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000155045#EAA_RS0216055
EAA_RS0216055 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000210455#CD7855_RS16190
CD7855_RS16190 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000211235#CDBI1_RS16095
CDBI1_RS16095 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000450145#QK3_RS16415
QK3_RS16415 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000450765#QO5_RS16755
QO5_RS16755 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000450785#QO7_RS16220
QO7_RS16220 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000451065#QSC_RS15880
QSC_RS15880 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000451785#QSO_RS15850
QSO_RS15850 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000451885#QU5_RS15935
QU5_RS15935 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000530295#BN174_RS15600
BN174_RS15600 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000530795#BN175_RS15735
BN175_RS15735 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000531255#BN173_RS15600
BN173_RS15600 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_000826625#BN2378_RS05485
BN2378_RS05485 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_001484885#CD26A54R_RS16050
CD26A54R_RS16050 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_001484895#CD26A54S_RS16165
CD26A54S_RS16165 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_001857645#HMPREF3082_RS07255
HMPREF3082_RS07255 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_001971835#BER28_RS16520
BER28_RS16520 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_001971865#BER27_RS16825
BER27_RS16825 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_001972015#BER29_RS16450
BER29_RS16450 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002300855#BGT96_RS04370
BGT96_RS04370 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002301165#BGU11_RS07575
BGU11_RS07575 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002301255#BGU15_RS05340
BGU15_RS05340 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002301525#BGU28_RS03770
BGU28_RS03770 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002301945#BGU80_RS00675
BGU80_RS00675 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002302755#BGV00_RS02440
BGV00_RS02440 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002302765#BGV01_RS00745
BGV01_RS00745 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002303105#BGV21_RS00045
BGV21_RS00045 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002303165#BGV24_RS08115
BGV24_RS08115 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002335485#NCKUH21_RS15905
NCKUH21_RS15905 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002812585#CWR57_RS16135
CWR57_RS16135 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002891495#AMR93_RS04205
AMR93_RS04205 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002891615#AMR88_RS00815
AMR88_RS00815 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002891625#AMR90_RS09680
AMR90_RS09680 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002945415#C3W74_RS16610
C3W74_RS16610 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002945515#C3L34_RS17090
C3L34_RS17090 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002945665#C3347_RS16605
C3347_RS16605 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002945755#C3348_RS16615
C3348_RS16615 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002945855#C3350_RS16620
C3350_RS16620 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002945945#C3349_RS16610
C3349_RS16610 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002946035#C3351_RS16620
C3351_RS16620 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002946135#C3352_RS16615
C3352_RS16615 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002946195#C3353_RS16605
C3353_RS16605 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002954285#AMR92_RS09045
AMR92_RS09045 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30
GCF_002954305#AMR91_RS05345
AMR91_RS05345 · HK · Classic
RefSeq: WP_009891645.1
UniProt: A0A0H3NB30

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003597795
AssemblyASM359779v1 · Chromosomehaploid
Genome composition4 221 948 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key