Gene detail

DA426_RS02540

Histidine kinase, Classic

Clostridioides difficile · GCF_003597795

ClassHKTypeClassicLength371 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_003597795#DA426_RS02540Stable P2CS identifier used across views.
GenomeGCF_003597795Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_2676088Run 6 · 404 sequences · id 100% · cov 80%
External referencesWP_009891726.1 · A0AB74R1N1 · MIST4 DA426_RS02540RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length371 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage173 / 371 aa (46.6%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa371 aa
HisKA: 148-211 aa (64 aa)1HATPase_c: 260-368 aa (109 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
148-211 aa · 64 aa · 17.3% of protein
Raw tokenHisKA:148:0.00000000000008:211:64:64
2 HATPase_c#2
260-368 aa · 109 aa · 29.4% of protein
Raw tokenHATPase_c:260:4.62e-25:368:110:109
  • Raw architecture: HisKA:148:0.00000000000008:211:64:64#HATPase_c:260:4.62e-25:368:110:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_003597795::NZ_CP028526.1::G00007
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span515121-520846Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA426_02540RefSeq proteinWP_009891726.1
Context group IDGCF_003597795::NZ_CP028526.1::G00007
Context members
DA426_RS02520DA426_RS02525DA426_RS02530DA426_RS02535DA426_RS02540
Partner locus tags
DA426_RS02520DA426_RS02525DA426_RS02530DA426_RS02535DA426_RS02540
Partner old locus tags
DA426_02520DA426_02525DA426_02530DA426_02535DA426_02540

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009891726.1Primary protein accession used for annex mappings.
UniProt accessionA0AB74R1N1Primary UniProt accession resolved in the annex database.
UniProt IDA0AB74R1N1_CLODIDisplay identifier provided by UniProt.
GO / PubMed5 / 0Unique GO terms and literature references available below.

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA426_RS02540Primary locus identifier stored in the genes table.
Old locus tagDA426_02540Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP028526.1Sequence record reported by the local genomic context database.
Genomic interval519 731-520 846 nt1 116 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span515 121-520 846 ntGCF_003597795::NZ_CP028526.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003597795::NZ_CP028526.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP028526.1All displayed genes belong to this local TCS context.
Neighborhood span515 121-520 846 nt5 726 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
515 121 nt520 846 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

DA426_RS02520GCF_003597795#DA426_RS02520
RROmpR

515 121-515 798 nt · Forward (+)

Old locus DA426_02520RefSeq WP_009891739.1
DA426_RS02525GCF_003597795#DA426_RS02525
HKClassic

515 870-517 885 nt · Forward (+)

Old locus DA426_02525RefSeq WP_009893921.1
DA426_RS02530GCF_003597795#DA426_RS02530
RROmpR

517 935-518 615 nt · Forward (+)

Old locus DA426_02530RefSeq WP_009891737.1
DA426_RS02535GCF_003597795#DA426_RS02535
RROmpR

518 997-519 695 nt · Forward (+)

Old locus DA426_02535RefSeq WP_009891729.1
DA426_RS02540GCF_003597795#DA426_RS02540
HKClassicCurrent focus

519 731-520 846 nt · Forward (+)

Old locus DA426_02540RefSeq WP_009891726.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_2676088Run 6 · HK · 404 sequences
Representative sequenceGCF_000003215#QAC_RS0216515Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_2676088

Simplified PFAM architecture for HKOC_2676088

PFAM domain coverage: 174 / 371 aa (46.9%)

1 aa371 aa
HisKA: 149-213 aaHisKAHATPase_c: 261-369 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[149-213] | HATPase_c[261-369]
  • Domain count: 2
  • Matched identifier: HKOC_2676088
  • Positioned domains: HisKA 149-213 ; HATPase_c 261-369
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0216515

Sankey plot built from the taxonomy of all members in the selected cluster.

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003597795
AssemblyASM359779v1 · Chromosomehaploid
Genome composition4 221 948 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key