Gene detail

DA426_RS02525

Histidine kinase, Classic

Clostridioides difficile · GCF_003597795

ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_003597795#DA426_RS02525Stable P2CS identifier used across views.
GenomeGCF_003597795Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Selected clusterHKOC_0842418Run 6 · 344 sequences · id 100% · cov 80%
External referencesWP_009893921.1 · A0A0H3NB90 · MIST4 DA426_RS02525RefSeq · UniProt · MIST4

Domain signature

Compact overview inferred from the domain field

HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Native P2CS viewFrontend rendering from the parsed domain string and TMPRED protein features.
1 aa671 aa
HisKA: 449-514 aa (66 aa)1HATPase_c: 565-668 aa (104 aa)2
Domain-by-domain annotation2 items
1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw tokenHisKA:449:0.00000000911:514:66:64
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw tokenHATPase_c:565:2.91e-30:668:104:109
  • Raw architecture: HisKA:449:0.00000000911:514:66:64#HATPase_c:565:2.91e-30:668:104:109
  • Domain description: 1 HisKA,1 HATPase_c
  • TM description: N/A
  • TMPRED source: No TMPRED file loaded
  • TMPRED segments: N/A
  • Complete: Yes

Context mapping

Resolved via p2cs_tcs_context.db when a locus tag match exists

Context labelpentadGCF_003597795::NZ_CP028526.1::G00007
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span515121-520846Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA426_02525RefSeq proteinWP_009893921.1
Context group IDGCF_003597795::NZ_CP028526.1::G00007
Context members
DA426_RS02520DA426_RS02525DA426_RS02530DA426_RS02535DA426_RS02540
Partner locus tags
DA426_RS02520DA426_RS02525DA426_RS02530DA426_RS02535DA426_RS02540
Partner old locus tags
DA426_02520DA426_02525DA426_02530DA426_02535DA426_02540

External references

Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table

RefSeqWP_009893921.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3NB90Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3NB90_CLODCDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
PubMed

Genomic coordinates

Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table

Current locus tagDA426_RS02525Primary locus identifier stored in the genes table.
Old locus tagDA426_02525Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP028526.1Sequence record reported by the local genomic context database.
Genomic interval515 870-517 885 nt2 016 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span515 121-520 846 ntGCF_003597795::NZ_CP028526.1::G00007

Local neighborhood

Graphical neighborhood resolved from the local TCS context group on the current contig

GCF_003597795::NZ_CP028526.1::G00007

Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.

Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP028526.1All displayed genes belong to this local TCS context.
Neighborhood span515 121-520 846 nt5 726 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
515 121 nt520 846 nt
Neighborhood gene cards

5 genes in the current local neighborhood.

DA426_RS02520GCF_003597795#DA426_RS02520
RROmpR

515 121-515 798 nt · Forward (+)

Old locus DA426_02520RefSeq WP_009891739.1
DA426_RS02525GCF_003597795#DA426_RS02525
HKClassicCurrent focus

515 870-517 885 nt · Forward (+)

Old locus DA426_02525RefSeq WP_009893921.1
DA426_RS02530GCF_003597795#DA426_RS02530
RROmpR

517 935-518 615 nt · Forward (+)

Old locus DA426_02530RefSeq WP_009891737.1
DA426_RS02535GCF_003597795#DA426_RS02535
RROmpR

518 997-519 695 nt · Forward (+)

Old locus DA426_02535RefSeq WP_009891729.1
DA426_RS02540GCF_003597795#DA426_RS02540
HKClassic

519 731-520 846 nt · Forward (+)

Old locus DA426_02540RefSeq WP_009891726.1

Clusters

CD-HIT memberships and selected cluster details for the current gene class

Selected clusterHKOC_0842418Run 6 · HK · 344 sequences
Representative sequenceGCF_000003215#QAC_RS0216530Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.

PFAM architecture for HKOC_0842418

Simplified PFAM architecture for HKOC_0842418

PFAM domain coverage: 170 / 671 aa (25.3%)

1 aa671 aa
HisKA: 450-514 aaHisKAHATPase_c: 563-667 aaHATPase_c
HisKAHATPase_c
  • Simplified architecture: HisKA + HATPase_c
  • Raw architecture: HisKA[450-514] | HATPase_c[563-667]
  • Domain count: 2
  • Matched identifier: HKOC_0842418
  • Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Visualization

Representative gene: GCF_000003215#QAC_RS0216530

Displayed with 5 columns and 10 rows per page from the local display config.

Showing members 1 to 50 over 344 total members. Page 1 / 7.

GCF_000003215#QAC_RS0216530 (representative)
QAC_RS0216530 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_000027105#CDR20291_RS16845
CDR20291_RS16845 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_000085225#CD196_RS16575
CD196_RS16575 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_000154645#UAA_RS0218430
UAA_RS0218430 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_000154665#QAD_RS0216625
QAD_RS0216625 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_000154685#AEC_RS0217995
AEC_RS0217995 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_000155045#EAA_RS0216425
EAA_RS0216425 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_000210455#CD7855_RS16530
CD7855_RS16530 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_000211235#CDBI1_RS16435
CDBI1_RS16435 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_000450765#QO5_RS17105
QO5_RS17105 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_000451065#QSC_RS16225
QSC_RS16225 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_000451785#QSO_RS16195
QSO_RS16195 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_000451885#QU5_RS16280
QU5_RS16280 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_000826625#BN2378_RS05830
BN2378_RS05830 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_001484885#CD26A54R_RS16395
CD26A54R_RS16395 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_001484895#CD26A54S_RS16510
CD26A54S_RS16510 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_001857645#HMPREF3082_RS06635
HMPREF3082_RS06635 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_001971835#BER28_RS16880
BER28_RS16880 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_001972015#BER29_RS16810
BER29_RS16810 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002301945#BGU80_RS01030
BGU80_RS01030 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002302755#BGV00_RS02085
BGV00_RS02085 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002302765#BGV01_RS00390
BGV01_RS00390 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002303165#BGV24_RS14055
BGV24_RS14055 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002335485#NCKUH21_RS16260
NCKUH21_RS16260 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002812585#CWR57_RS16495
CWR57_RS16495 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002945415#C3W74_RS16970
C3W74_RS16970 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002945515#C3L34_RS17450
C3L34_RS17450 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002945665#C3347_RS16965
C3347_RS16965 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002945755#C3348_RS16975
C3348_RS16975 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002945855#C3350_RS16980
C3350_RS16980 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002945945#C3349_RS16970
C3349_RS16970 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002946035#C3351_RS16980
C3351_RS16980 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002946135#C3352_RS16975
C3352_RS16975 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002946195#C3353_RS16965
C3353_RS16965 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_002954285#AMR92_RS08155
AMR92_RS08155 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003313545#CDIF27638_RS16980
CDIF27638_RS16980 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003313585#CDIF27640_RS16970
CDIF27640_RS16970 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003482035#CDIF28196_RS17315
CDIF28196_RS17315 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003597795#DA426_RS02525
DA426_RS02525 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003597815#DA430_RS16975
DA430_RS16975 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003597835#DA432_RS16830
DA432_RS16830 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003597895#DA422_RS17150
DA422_RS17150 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003597915#DA436_RS17110
DA436_RS17110 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003625415#C0215_RS03005
C0215_RS03005 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003625425#C0983_RS15310
C0983_RS15310 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003625435#C0984_RS01040
C0984_RS01040 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003862685#EGM06_RS05345
EGM06_RS05345 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003863035#EGL82_RS01040
EGL82_RS01040 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003863055#EGM11_RS04295
EGM11_RS04295 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90
GCF_003863075#EGL79_RS02935
EGL79_RS02935 · HK · Classic
RefSeq: WP_009893921.1
UniProt: A0A0H3NB90

Genome taxonomy

Unknown

Taxonomy recordUnknownTaxon ID 1 496 · GCF_003597795
AssemblyASM359779v1 · Chromosomehaploid
Genome composition4 221 948 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides

Related genes

Preview from the same derived genome key