1 HisKA#1
449-514 aa · 66 aa · 9.8% of protein
Raw token
HisKA:449:0.00000000911:514:66:64P2CS-Web
Two-component systems, rebuilt for exploration
Gene detail
DA426_RS02525
Histidine kinase, Classic
Clostridioides difficile · GCF_003597795
ClassHKTypeClassicLength671 aaTM0ValidatedNoCompleteYesContextpentad
Gene IDGCF_003597795#DA426_RS02525Stable P2CS identifier used across views.
GenomeGCF_003597795Bacteria; Bacillati; Bacillota; Clostridia; Peptostreptococcales; Peptostreptococcaceae; Clostridioides
Domain signature
Compact overview inferred from the domain field
HisKAHATPase_c
Protein length671 aaLength used to scale native and Biotite-like views.
Annotated domains22 with usable coordinates.
Domain coverage170 / 671 aa (25.3%)Merged over positioned domains only.
Domain description1 HisKA,1 HATPase_cSummary string stored in the genes table.
Signal peptideUnavailableNo TMPRED prediction file matched this gene.
Transmembrane helicesUnavailableConfigure [protein_features] tmpred_root_dir to enable this annotation.
Complete domain annotations
Biotite-like viewServer-side Python rendering inspired by the Biotite sigma-domain example.
Domain-by-domain annotation2 items
2 HATPase_c#2
565-668 aa · 104 aa · 15.5% of protein
Raw token
HATPase_c:565:2.91e-30:668:104:109- Raw architecture: HisKA:449:0.00000000911:514:66:64#HATPase_c:565:2.91e-30:668:104:109
- Domain description: 1 HisKA,1 HATPase_c
- TM description: N/A
- TMPRED source: No TMPRED file loaded
- TMPRED segments: N/A
- Complete: Yes
Context mapping
Resolved via p2cs_tcs_context.db when a locus tag match exists
Context labelpentadGCF_003597795::NZ_CP028526.1::G00007
Group size55 locus tags listed below.
HK / RR2 / 3Counts resolved for the local TCS neighborhood.
Context span515121-520846Genomic interval covered by the local TCS group.
Identifiers
Old locus tagDA426_02525RefSeq proteinWP_009893921.1
Context group ID
GCF_003597795::NZ_CP028526.1::G00007Context members
DA426_RS02520DA426_RS02525DA426_RS02530DA426_RS02535DA426_RS02540
Partner locus tags
DA426_RS02520DA426_RS02525DA426_RS02530DA426_RS02535DA426_RS02540
Partner old locus tags
DA426_02520DA426_02525DA426_02530DA426_02535DA426_02540
Partner protein IDs
External references
Resolved via p2cs_annexes.db when the RefSeq protein is present in the annex table
RefSeqWP_009893921.1Primary protein accession used for annex mappings.
UniProt accessionA0A0H3NB90Primary UniProt accession resolved in the annex database.
UniProt IDA0A0H3NB90_CLODCDisplay identifier provided by UniProt.
GO / PubMed5 / 1Unique GO terms and literature references available below.
Reference hubs
PubMed
Genomic coordinates
Resolved via p2cs_tcs_context.db when the current locus tag is present in the local context table
Current locus tagDA426_RS02525Primary locus identifier stored in the genes table.
Old locus tagDA426_02525Legacy locus tag recovered from the local context mapping.
Contig / repliconNZ_CP028526.1Sequence record reported by the local genomic context database.
Genomic interval515 870-517 885 nt2 016 nt · Forward (+)
StrandForward (+)Strand sign follows the local context database convention.
Local TCS group span515 121-520 846 ntGCF_003597795::NZ_CP028526.1::G00007
Quick actions
Local neighborhood
Graphical neighborhood resolved from the local TCS context group on the current contig
GCF_003597795::NZ_CP028526.1::G00007Graphic view
Compact keeps a quick overview. Biotite-like switches to a coordinate-aware biological layout with strand and zoom.
Context labelpentadNeighborhood members are ordered by genomic coordinates.
Contig / repliconNZ_CP028526.1All displayed genes belong to this local TCS context.
Neighborhood span515 121-520 846 nt5 726 nt
Members51 current focus gene
Local TCS group mapArrow direction follows strand. The current gene is highlighted with a stronger outline.
515 121 nt520 846 nt
Neighborhood gene cards
5 genes in the current local neighborhood.
DA426_RS02520GCF_003597795#DA426_RS02520
RROmpR
515 121-515 798 nt · Forward (+)
DA426_RS02525GCF_003597795#DA426_RS02525
HKClassicCurrent focus
515 870-517 885 nt · Forward (+)
DA426_RS02530GCF_003597795#DA426_RS02530
RROmpR
517 935-518 615 nt · Forward (+)
DA426_RS02535GCF_003597795#DA426_RS02535
RROmpR
518 997-519 695 nt · Forward (+)
DA426_RS02540GCF_003597795#DA426_RS02540
HKClassic
519 731-520 846 nt · Forward (+)
Clusters
CD-HIT memberships and selected cluster details for the current gene class
Available memberships1 cluster
Representative sequenceGCF_000003215#QAC_RS0216530Use this link to inspect the representative gene detail.
PFAM architectureHisKA + HATPase_c2 domains in the representative PFAM annotation.
PFAM architecture for HKOC_0842418
Simplified PFAM architecture for HKOC_0842418
PFAM domain coverage: 170 / 671 aa (25.3%)
1 aa671 aa
HisKAHATPase_c
- Simplified architecture: HisKA + HATPase_c
- Raw architecture: HisKA[450-514] | HATPase_c[563-667]
- Domain count: 2
- Matched identifier: HKOC_0842418
- Positioned domains: HisKA 450-514 ; HATPase_c 563-667
Cluster members and taxonomy
Representative gene: GCF_000003215#QAC_RS0216530
Sankey plot built from the taxonomy of all members in the selected cluster.
Genome taxonomy
Unknown
Taxonomy recordUnknownTaxon ID 1 496 · GCF_003597795
AssemblyASM359779v1 · Chromosomehaploid
Genome composition4 221 948 bp · 29,0% GCClostridioides difficile
Signal transduction countsGenes 105 · HK 50 · RR 55CheA 1 · PP 0
Ranked taxonomy7 ranked levels available
SuperkingdomBacteriaKingdomBacillatiPhylumBacillotaClassClostridiaOrderPeptostreptococcalesFamilyPeptostreptococcaceaeGenusClostridioides
Lineage path7 lineage nodes
1Bacteria2Bacillati3Bacillota4Clostridia5Peptostreptococcales6Peptostreptococcaceae7Clostridioides
Related genes
Preview from the same derived genome key